Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins?

Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins?

Shemirani H¹ ; Khanjani R² ; Mohammadisichani M³ ; Mozafarpour S⁴ ; Rabani M¹ ; Shahabi J⁵

Show Affiliations

1. Hypertension Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
2. Department of Internal Medicine, Isfahan Cardiovascular Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran
3. Department of Urology, Urology and Kidney Transplantation Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
4. Medical Student Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
5. Cardiac Rehabilitation Research Center, Isfahan Cardiovascular Research Institute, Isfahan University of Medical Sciences, Isfahan, Iran

Source: ARYA Atherosclerosis Published:2014

Abstract

BACKGROUND: Percutaneous nephrolithotomy is the treatment of choice in large and staghorn renal stones, and myocardial infarction is one the possible complications during and after the surgery. We investigated if renal and skeletal muscle injury, caused by percutaneous nephrolithotomy, can cause elevation in cardiac troponins (cTn). METHODS: This study was conducted on otherwise healthy patients with renal stone undergoing percutaneous nephrolithotomy. A baseline 12-lead electrocardiogram, echocardiography, and cTn assessment confirmed no cardiac pathology in any patients. Cardiac troponins T (cTnT) and I (cTnI), and also creatine kinase (CK) were assessed before and after surgery. RESULTS: A total of 55 patients (69.1% males, mean age: 40.5 ± 13.8 year) were included. Serum creatinine level ranged from 0.7 to 1.3 mg/dl (mean = 1.03 ± 0.17). The level of CK was significantly increased by 469.5 ± 201.4 U/l (P < 0.001), and no positive cTnT or cTnI was observed after surgery. CONCLUSION: The results of the present study showed that renal cell injury, caused by percutaneous nephrolithotomy, is not associated with elevated cardiac troponins. These findings show that increasing troponins in patients undergoing percutaneous nephrolithotomy indicate a cardiovascular pathology.

Related Docs

View other Related Docs

1. Evaluation of Troponin I Serum Level in Patients With Peritoneal Dialysis and Relationship Between Troponin I and Cardiovascular Risk Factors, Acta Medica Iranica (2019)

2. The Effect of Hemodialysis of on Serum Troponin I Level in Patients With Renal Disease and Normal Left Ventricular Ejection Fraction, Journal of Isfahan Medical School (2022)

3. Prevalence of Acute Kidney Injury Following Percutaneous Nephrolithotomy, Journal of Research in Medical Sciences (2024)

4. Possibility of Post Percutaneous Nephrolithotomy Renal Function Alterations Leading to Acute Kidney Injury, Translational Research in Urology (2023)

5. Investigation of Urinary Neutrophil Gelatinase Associated Lipocalin (Ngal) for Early Diagnosis of Acute Kidney Injury After Percutaneous Nephrolithotomy, African Journal of Urology (2017)

6. Association of Cardiac Troponin I Level With In-Hospital and Late Mortality in Dialysis Patients, Journal of Research in Medical Sciences (2025)

7. Percutaneous Nephrolithotomy Success Rate and Complications in Patients With Previous Open Stone Surgery, Urology Journal (2014)

8. Evaluation and Comparison of Metabolic Disorders Between Patients With Unilateral and Bilateral Staghorn Renal Stones, Urology journal (2019)

Experts (# of related papers)

View all Related Experts

Shahram Taheri (4)

Mehrdad Mohammadi Sichani (3)

Style	Citing Format
MLA	Shemirani H, et al.. "Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins?." ARYA Atherosclerosis, vol. 10, no. 1, 2014, pp. 41-45.
APA	Shemirani H, Khanjani R, Mohammadisichani M, Mozafarpour S, Rabani M, Shahabi J (2014). Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins?. ARYA Atherosclerosis, 10(1), 41-45.
Chicago	Shemirani H, Khanjani R, Mohammadisichani M, Mozafarpour S, Rabani M, Shahabi J. "Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins?." ARYA Atherosclerosis 10, no. 1 (2014): 41-45.
Harvard	Shemirani H et al. (2014) 'Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins?', ARYA Atherosclerosis, 10(1), pp. 41-45.
Vancouver	Shemirani H, Khanjani R, Mohammadisichani M, Mozafarpour S, Rabani M, Shahabi J. Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins?. ARYA Atherosclerosis. 2014;10(1):41-45.
BibTex	@article{ author = {Shemirani H and Khanjani R and Mohammadisichani M and Mozafarpour S and Rabani M and Shahabi J}, title = {Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins?}, journal = {ARYA Atherosclerosis}, volume = {10}, number = {1}, pages = {41-45}, year = {2014} }
RIS	TY - JOUR AU - Shemirani H AU - Khanjani R AU - Mohammadisichani M AU - Mozafarpour S AU - Rabani M AU - Shahabi J TI - Does Percutaneous Nephrolithotomy Cause Elevated Cardiac Troponins? JO - ARYA Atherosclerosis VL - 10 IS - 1 SP - 41 EP - 45 PY - 2014 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract