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Hypertrophic Cardiomyopathy Diagnosis Using Deep Learning Techniques Publisher



Sharifrazi D1 ; Alizadehsani R2 ; Izadi NH3 ; Roshanzamir M4 ; Shoeibi A5 ; Khozeimeh F2 ; Sani FA6 ; Sani ZA7 ; Hussain S8 ; Harlapur C9 ; Gorriz JM10, 11 ; Zhang YD12 ; Khosravi A2 ; Nahavandi S2 Show All Authors
Authors
  1. Sharifrazi D1
  2. Alizadehsani R2
  3. Izadi NH3
  4. Roshanzamir M4
  5. Shoeibi A5
  6. Khozeimeh F2
  7. Sani FA6
  8. Sani ZA7
  9. Hussain S8
  10. Harlapur C9
  11. Gorriz JM10, 11
  12. Zhang YD12
  13. Khosravi A2
  14. Nahavandi S2
  15. Sarrafzadegan N13, 14
  16. Islam SMS15, 16, 17
Show Affiliations
Authors Affiliations
  1. 1. Department of Computer Engineering, School of Technical and Engineering, Islamic Azad University, Shiraz Branch, Shiraz, Iran
  2. 2. Institute for Intelligent Systems Research and Innovation (IISRI), Deakin University, Geelong, Australia
  3. 3. Department of Electrical and Computer Engineering, Isfahan University of Technology, Isfahan, Iran
  4. 4. Department of Computer Engineering, Faculty of Engineering, Fasa University, Fasa, Iran
  5. 5. Data Science and Computational Intelligence Institute, University of Granada, Granada, Spain
  6. 6. Mashhad University of Medical Science, Mashhad, Iran
  7. 7. Department of Cardiac MRI, Omid Hospital, Tehran, Iran
  8. 8. System Administrator, Dibrugarh University, Assam, 786004, India
  9. 9. Emergency Department, Epworth Hospital, Geelong, Australia
  10. 10. Department of Signal Theory, Networking and Communications, Universidad de Granada, Spain
  11. 11. Department of Psychiatry, University of Cambridge, Cambridge, United Kingdom
  12. 12. Department of Informatics, University of Leicester, Leicester, United Kingdom
  13. 13. Faculty of Medicine, SPPH, University of British Columbia, Vancouver, BC, Canada
  14. 14. Isfahan Cardiovascular Research Center, Cardiovascular Research Institute, Isfahan University of Medical Sciences, Khorram Ave, Isfahan, Iran
  15. 15. Institute for Physical Activity and Nutrition, School of Exercise and Nutrition Sciences, Deakin University, Geelong, Australia
  16. 16. Cardiovascular Division, George Institute for Global Health, Newtown, Australia
  17. 17. Sydney Medical School, University of Sydney, Camperdown, Australia

Source: Human-centric Computing and Information Sciences Published:2024


Abstract

Hypertrophic cardiomyopathy (HCM), which can lead to serious cardiac problems, is often diagnosed using cardiovascular magnetic resonance (CMR) images obtained from patients. This research consisted in developing a deep learning technique to diagnose HCM, using a dataset consisting of 37,421 healthy and 21,846 HCM patients obtained over a period of two years. The proposed dataset is the largest publicly available CMR dataset for HCM diagnosis. Three experts inspected the images and determined whether each one showed a case of HCM or not. Novel data augmentation was used by employing color filtering. To classify the augmented images, a convolutional neural network (CNN) was designed and tuned. To the best of the authors’ knowledge, none of the existing studies have tackled HCM diagnosis based on CMR images, and this paper is the first one in this regard. Comparing the designed algorithm output with the experts’ opinions, the proposed method achieved accuracy of 98.53%, recall of 98.70%, and specificity of 95.21% on the augmented dataset. Experiments were also conducted with different optimizers and other methods of data augmentation to further evaluate the proposed method. Using the proposed data augmentation method, accuracy of 98.53% was achieved, which is higher than the best accuracy (95.83%) obtained by the other evaluated methods of data augmentation. The paper presents the theoretical performance bound of the proposed method, and a comparison with existing papers which reveals the superiority of the proposed approach in terms of various performance metrics. The advantages of the proposed method include the elimination of the contrast agent and its complications, a lower CMR examination time, and lower costs for patients and cardiac imaging centers. © (2024) Korea Information Processing Society.