Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients

Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients

Nilforoushzadeh MA¹ ; Siadat AH² ; Arianrad M³ ; Moulavi F^{4, 5} ; Haftbaradaran E³ ; Esfahani MHN^{4, 5}

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1. Head of Skin Diseases and Leishmaniasis Research Center (Sedigheh Tahereh), Tehran University of Medical Sciences, Tehran, Iran
2. Dermatologist, Skin Diseases and Leishmaniasis Research Center (Sedigheh Tahereh), Isfahan University of Medical Sciences, Isfahan, Iran
3. Skin Diseases and Leishmaniasis Research Center (Sedigheh Tahereh), Isfahan University of Medical Sciences, Isfahan, Iran
4. Rooyan Institute, Jahad Daneshgahi, Isfahan, Iran
5. Rooyan Institute, Jahad Daneshgahi, Isfahan, Iran

Source: Journal of Research in Medical Sciences Published:2010

Abstract

BACKGROUND: There are many filler agents for augmentation of static wrinkles and atrophic scars from synthetic, biosynthetic, cadaver, animal and human sources. METHODS: The current study presents 20 patients whose facial wrinkles and lines were treated by transplantation of autologous cultured fibroblasts. The fibroblast nature of cells was confirmed by immune-staining and flow cytometry. RESULTS: The mean of improvement for this procedure at the 6 month follow up was 41%. CONCLUSIONS: In conclusion autologous fibroblast transplantation can be an effective procedure for correction of wrinkles and atrophic scars.

2. Transplantation of Autologous Epidermal Melanocyte–Keratinocyte Cells Suspension for Cell Therapy of Vitiligo: A Clinical Evaluation and Biometric Assessment, Journal of Cosmetic Dermatology (2022)

3. Application of Allogeneic Fibroblast Cells in Cellular Therapy of Recessive Dystrophic Epidermolysis Bullosa, Journal of Skin and Stem Cell (2015)

Style	Citing Format
MLA	Nilforoushzadeh MA, et al.. "Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients." Journal of Research in Medical Sciences, vol. 15, no. 3, 2010, pp. 167-171.
APA	Nilforoushzadeh MA, Siadat AH, Arianrad M, Moulavi F, Haftbaradaran E, Esfahani MHN (2010). Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients. Journal of Research in Medical Sciences, 15(3), 167-171.
Chicago	Nilforoushzadeh MA, Siadat AH, Arianrad M, Moulavi F, Haftbaradaran E, Esfahani MHN. "Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients." Journal of Research in Medical Sciences 15, no. 3 (2010): 167-171.
Harvard	Nilforoushzadeh MA et al. (2010) 'Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients', Journal of Research in Medical Sciences, 15(3), pp. 167-171.
Vancouver	Nilforoushzadeh MA, Siadat AH, Arianrad M, Moulavi F, Haftbaradaran E, Esfahani MHN. Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients. Journal of Research in Medical Sciences. 2010;15(3):167-171.
BibTex	@article{ author = {Nilforoushzadeh MA and Siadat AH and Arianrad M and Moulavi F and Haftbaradaran E and Esfahani MHN}, title = {Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients}, journal = {Journal of Research in Medical Sciences}, volume = {15}, number = {3}, pages = {167-171}, year = {2010} }
RIS	TY - JOUR AU - Nilforoushzadeh MA AU - Siadat AH AU - Arianrad M AU - Moulavi F AU - Haftbaradaran E AU - Esfahani MHN TI - Soft Tissue Augmentation by Autologous Cultured Fibroblasts Transplantation for Treatment of Wrinkles and Scars: A Case Series of 20 Patients JO - Journal of Research in Medical Sciences VL - 15 IS - 3 SP - 167 EP - 171 PY - 2010 ER -

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