Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Health-Related Quality of Life and Its Related Factors in Patients With Systemic Lupus Erythematosus in Southwest Iran: A Cross-Sectional Study Publisher Pubmed



Hashemi S1 ; Farahbakhsh S2 ; Aghakhani Z3 ; Momayezanmarnani A4 ; Hemati N5 ; Hashemi S1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Internal Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
  2. 2. Occupational Therapy, Zanjan University of Medical Sciences, Zanjan, Iran
  3. 3. Science, York University, Toronto, Canada
  4. 4. Nursing, Isfahan University of Medical Sciences, Isfahan, Iran
  5. 5. Clinical Exercise Physiology, Shiraz University, Shiraz, Iran

Source: BMC Psychology Published:2023


Abstract

Background: Quality of life (QoL) is an important measure in health assessment. It is impacted by unclear factors in Systemic Lupus Erythematosus (SLE) patients. The study aimed to investigate the factors related to QoL in SLE patients. Methods: This cross-sectional study was performed on 140 (136 women and four men) Iranian SLE patients of Hafiz Hospital from June 2019 to August 2020. The Lupus Erythematosus Quality of Life Questionnaire (LEQoL) was used to evaluate the quality of life. The patients were evaluated with this questionnaire for four weeks in eight dimensions health, emotional health, body image, pain, planning, intimate relationships, and the burden of others. Related factors of LEQoL were evaluated using multivariable linear regression. Results: The mean age was 34.09(8.96) years. The total mean QoL Score was 65.5 ± 22.4. The multivariable analysis showed that duration of disease (β:-1.12, 95% CI:-1.44 to -0.79, P:0.001), physical activity(β:-12.99, 95% CI:-19.2 to -6.13, P:0.001), kidney involvement (β:-9.2, 95% CI:-16.61 to -2.79, P:0.03) and skin involvement(β:-8.7, 95% CI:-17.2 to -0.2, P:0.031) were significantly related to the total mean QOL score of SLE patients. Conclusion: The QoL of Iranian patients with SLE was low. Age and gender can be related to the decrease in the QoL of patients with SLE. Increasing the disease duration, physical activity, kidney involvement, and skin involvement can be related to the decrease in the QOL of Iranian patients with SLE. © 2023, BioMed Central Ltd., part of Springer Nature.
Related Docs
View other Related Docs
1. Evaluating the Validity and Reliability of Persian Version of Lupus Quality of Life (Lupusqol) Questionnaire in Iranian Patients, Journal of Isfahan Medical School (2014)
2. Linguistic Validation of the Lupusqol for the Assessment of Quality of Life in Iranian Patients With Systemic Lupus Erythematosus, International Journal of Rheumatology (2014)
3. Sleep Quality in Women With Systemic Lupus Erythematosus: Contributing Factors and Effects on Health-Related Quality of Life, International Journal of Rheumatic Diseases (2016)
4. Predictors of Health-Related Quality of Life Among Iranian People With Type 2 Diabetes, Journal of Nephropharmacology (2023)
5. Metabolic Syndrome in Iranian Patients With Systemic Lupus Erythematosus and Its Determinants, Clinical Rheumatology (2018)
6. Sleep Disorders in Systemic Lupus Erythematosus Does Vitamin D Play a Role?, Lupus (2014)
7. Correlation of Lupus Activity Based on British Isles Lupus Assessment Group Index With Serologic Markers of Lupus Activity in Patients of Rheumatology Clinic, Journal of Isfahan Medical School (2010)
8. Correlation of Esr, C3, C4, Anti-Dna and Lupus Activity Based on British Isles Lupus Assessment Group Index in Patients of Rheumatology Clinic, Rheumatology International (2010)
Experts (# of related papers)
View all Related Experts
Alimohammad Fatemi (9)
Mansoor Karimifar (4)
Other Related Docs
9. Effects of a Comprehensive Cardiac Rehabilitation Program on Quality of Life in Patients With Coronary Artery Disease, ARYA Atherosclerosis (2013)
10. Long-Term Follow-Up of Iranian Male Patients With Systemic Lupus Erythematosus, Clinical and Experimental Medicine (2023)
11. The Validity and Reliability of the Persian Version of Kidney Disease Quality of Life Questionnaire-Short Form (Kdqol-Sf) in Iranian Patients, Journal of Isfahan Medical School (2012)
12. Quality of Life in Peptic Ulcer Patients Referring to Al-Zahra Hospital of Isfahan, Iran, Gastroenterology and Hepatology from Bed to Bench (2013)
13. Comparative Study of Quality of Life, Anxiety, Depression, and Fatigue Among Patients With Neuromyelitis Optica Spectrum Disorder and Multiple Sclerosis: The First Report From Iran, Multiple Sclerosis and Related Disorders (2018)
14. Fatigue, Depression, and Health-Related Quality of Life in Patients With Multiple Sclerosis in Isfahan, Iran, European Journal of Neurology (2012)
15. Psychometric Properties of the Whoqol-Bref in an Iranian Adult Sample, Community Mental Health Journal (2010)
16. Development of the European Organisation for Research and Treatment of Cancer Quality of Life Questionnaire Module for Older People With Cancer: The Eortc Qlq-Eld15, European Journal of Cancer (2010)
17. Chronic Patients' Activation and Its Association With Stress, Anxiety, Depression, and Quality of Life: A Survey in Southeast Iran, BioMed Research International (2021)
18. Investigating the Correlation Between Health-Promoting Lifestyle and Health Hardiness With Quality of Life, BMC Psychology (2024)
19. How Different Domains of Quality of Life Are Associated With Latent Dimensions of Mental Health Measured by Ghq-12, Health and Quality of Life Outcomes (2021)
20. The Association Between Initial Manifestations of Childhood-Onset Systemic Lupus Erythematosus and the Survival, International Journal of Rheumatic Diseases (2016)
21. Prognostic Factors of Mortality in Iranian Patients With Systemic Lupus Erythematosus Admitted to Intensive Care Unit, Clinical Rheumatology (2017)
22. Childhood Versus Adult-Onset Systemic Lupus Erythematosus: Long-Term Outcome and Predictors of Mortality, Clinical Rheumatology (2017)
23. Development and Validation of the Stressful Life Event Questionnaire, International Journal of Public Health (2011)
24. Long-Term Outcome of Biopsy-Proven Lupus Nephritis in Iran, International Journal of Rheumatic Diseases (2013)
25. The Use of Pharmaceutical Care to Improve Health-Related Quality of Life in Hemodialysis Patients in Iran, International Journal of Clinical Pharmacy (2013)
26. Sensitivity Analyses of Four Systemic Lupus Erythematosus Disease Activity Indices in Predicting the Treatment Changes in Consecutive Visits: A Longitudinal Study, Clinical Rheumatology (2018)
27. Socio-Economic Inequalities in Health-Related Quality of Life Among Iranian Young People in the Middle Stage of Adolescence: Application of Health Equity Assessment Toolkit, BMC Pediatrics (2023)
28. Personality Traits and Quality of Life: A Cross-Sectional Study in a Middle-Aged Iranian General Population, Health and Quality of Life Outcomes (2025)
29. Persian Version of the Brief Older People's Quality of Life Questionnaire (Opqol-Brief): The Evaluation of the Psychometric Properties, Health and Quality of Life Outcomes (2020)
30. Quality of Life Assessment in Pre-Hospital and Hospital Emergency Healthcare Workers: A Pilot Study, Australasian Journal of Paramedicine (2021)
31. Outcome of Adult Onset Systemic Lupus Erythematosus in Iran, Lupus (2014)
32. Clinical and Laboratory Signs Among Systemic Lupus Erythematosus Patients in Isfahan, Journal of Isfahan Medical School (2012)
33. Evaluation of Damage Index and Its Association With Risk Factors in Patients With Systemic Lupus Erythematosus, Journal of Research in Medical Sciences (2011)
34. Comparison of Health-Related Quality of Life After Percutaneous Coronary Intervention and Coronary Artery Bypass Surgery, ARYA Atherosclerosis (2016)
35. Respiratory Muscle Function and Spirometry in Patients With Systemic Lupus Erythematosus, Tanaffos (2006)