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The Importance of Stem Cells in the Treatment of Neuropathic Pain Publisher Pubmed



Fh Kiabi Farshad HASANZADEH ; T Khosravi TAYEBEH ; Sg Ahangar Saeed GHAROOEE ; S Beiranvand SIAVASH
Authors

Source: Central Nervous System Agents in Medicinal Chemistry Published:2025


Abstract

Many disorders, including heart, bone, cancer, liver, and brain disease, have been treated using stem cell therapy as a viable alternative. The somatosensory system is affected by a lesion, which leads to neuropathic pain (NP), and just a relatively tiny fraction of patients now receive effective care from existing pharmacological medications. There have been studies to show the effectiveness of various stem cells in reducing or treating experimental neurological pain, although these studies are uncommon in number. In this narrative review, we will summarize the preclinical and clinical research that has been conducted on the effectiveness of several stem cell types, such as mesenchymal stem cells, bone-derived stem cells, and neural stem cells, in reducing neurological pain in this study. © 2025 Elsevier B.V., All rights reserved.