Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
The Association Between Dietary Polyphenol Intake and Attention-Deficit Hyperactivity Disorder: A Case-Control Study Publisher Pubmed



Darzi M1 ; Abbasi K2 ; Ghiasvand R2 ; Akhavan Tabib M3 ; Rouhani MH2
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Nutrition, Science and Research Branch, Islamic Azad University, Tehran, Iran
  2. 2. Nutrition and Food Security Research Center, Department of Community Nutrition, School of Nutrition and Food Science, Isfahan University of Medical Sciences, Isfahan, Iran
  3. 3. Learning Center, West LA College, Los Angeles, United States

Source: BMC Pediatrics Published:2022


Abstract

Background: Previous research found that diets high in fruits and vegetables improved symptoms of attention deficit hyperactivity disorder (ADHD). Nevertheless, the relationship between dietary polyphenol intake and the risk of ADHD was not assessed. Objective: The purpose of this study was to see if there was a relationship between dietary polyphenol intake and the risk of ADHD in children in preschool and elementary school. Methods: A total of 400 children aged 4 to 12 years old participated in this case-control research (200 children with diagnosed ADHD and 200 healthy controls). The presence of ADHD was diagnosed according to the Diagnostic and Statistical Manual of Mental Disorders-V criteria. To calculate dietary polyphenol intake, a 168-item food frequency questionnaire and the Phenol-Explorer database were used. Results: A significant negative association was observed between one unit increase in dietary polyphenol intake and risk of ADHD (OR: 0.995, 95% CI = 0.994 to 0.996, P < 0.001) in the crude model. This finding was still significant even after adjusting for body mass index, energy intake, socioeconomic status, gender, and age (OR: 0.992, 95% CI = 0.989 to 0.995, P < 0.001). Conclusion: We found that the increased dietary intake of polyphenols is associated with a lower risk of ADHD in preschool and school children. Prospective studies are needed to corroborate these observations. © 2022, The Author(s).
Related Docs
View other Related Docs
1. A Plant-Based Dietary Score and Attention Deficit/Hyperactivity Disorder in Iranian Children: A Case-Control Study, Journal of Affective Disorders (2022)
2. Dietary Phytochemical Index and Attention-Deficit/Hyperactivity Disorder in Iranian Children: A Case Control Study, European Journal of Clinical Nutrition (2022)
3. Dietary Patterns and Attention Deficit Hyperactivity Disorder Among Iranian Children: A Case-Control Study, Journal of the American College of Nutrition (2019)
4. Adherence to Mediterranean Diet and Attention-Deficit/Hyperactivity Disorder in Children: A Case Control Study, Clinical Nutrition ESPEN (2022)
5. Diet Cost Plays a Key Role in Determining the Risk of Pediatric Attention Deficit Hyperactivity Disorder: Findings From a Case–Control Study, Food Science and Nutrition (2022)
6. Dietary Patterns and Attention Deficit Hyperactivity Disorder Among Iranian Children, Nutrition (2012)
7. The Association Between Dietary Acid Load and Risk of Attention-Deficit Hyperactivity Disorder: A Case-Control Study, Child Neuropsychology (2023)
8. The Effects of Vitamin D Supplementation on the Antioxidant Serum Level in 6-13 Years Old Children With Adhd, Tehran University Medical Journal (2017)
Experts (# of related papers)
View all Related Experts
Roya Kelishadi (28)
Awat Feizi (11)
Other Related Docs
9. The Relationship Between Antioxidants and Inflammation in Children With Attention Deficit Hyperactivity Disorder, Basic and Clinical Neuroscience (2020)
10. Relationship Between Antioxidant Status and Attention Deficit Hyperactivity Disorder Among Children, International Journal of Preventive Medicine (2019)
11. Association of Healthy Food Intake With Psychiatric Distress in Children and Adolescents: The Caspian-Iv Study, International Journal of Pediatrics (2016)
12. Evaluating the Association Between the Mediterranean-Dash Intervention for Neurodegenerative Delay (Mind) Diet, Mental Health, and Cardio-Metabolic Risk Factors Among Individuals With Obesity, BMC Endocrine Disorders (2023)
13. Do Patterns of Nutrient Intake Predict Self-Reported Anxiety, Depression and Psychological Distress in Adults? Sepahan Study, Clinical Nutrition (2019)
14. Dietary Phytochemical Index in Relation to Metabolic Health Status, Serum Adropin, and Brain-Derived Neurotrophic Factor Levels in Adults, Current Developments in Nutrition (2024)
15. The Association Between Stress Levels and Food Consumption Among Iranian Population, Archives of Iranian Medicine (2013)
16. Potato Consumption As High Glycemic Index Food, Blood Pressure, and Body Mass Index Among Iranian Adolescent Girls, ARYA Atherosclerosis (2015)
17. The Relationship Between Dietary Patterns and Metabolic Phenotypes: A Cross-Sectional Study in a Representative Sample of Iranian Industrial Employees, Metabolic Syndrome and Related Disorders (2024)
18. Association of Sleep Duration and Snack Consumption in Children and Adolescents: The Caspian-V Study, Food Science and Nutrition (2020)
19. The Association of Ultra-Processed Food Consumption With Adult Mental Health Disorders: A Systematic Review and Dose-Response Meta-Analysis of 260,385 Participants, Nutritional Neuroscience (2023)
20. Association of Healthy Foods Intake With Anthropometric Measures and Blood Pressure in a National Sample of Iranian Children and Adolescents: The Caspian-Iv Study, Minerva Pediatrica (2019)
21. Association of Vitamin D Concentrations With Subjective Health Complaints in Children and Adolescents: The Caspian-V Study, BMC Public Health (2021)
22. The Association Between Autism Spectrum Disorders and Dietary Intake of Carbohydrates in School-Aged Children in Iran: A Case–Control Study, Neuropsychopharmacology Reports (2025)
23. Association of Exposure to Bisphenol a With Obesity and Cardiometabolic Risk Factors in Children and Adolescents, International Journal of Environmental Health Research (2019)
24. Association Between Junk Food Consumption and Cardiometabolic Risk Factors in a National Sample of Iranian Children and Adolescents Population: The Caspian-V Study, Eating and Weight Disorders (2020)
25. Effect of Vitamin D and Magnesium Supplementation on Behavior Problems in Children With Attention-Deficit Hyperactivity Disorder, International Journal of Preventive Medicine (2020)
26. Higher Dietary Phytochemical Index Is Associated With Anthropometric Indices in Children and Adolescents: The Weight Disorders Survey of the Caspian-Iv Study, International Journal for Vitamin and Nutrition Research (2021)
27. Investigation of Adherence to Dash Diet Components and Reduction of Heart Failure Risk in Adults: A Case-Control Study, ARYA Atherosclerosis (2024)
28. The Effects of Vitamin D Supplementation on Adhd (Attention Deficit Hyperactivity Disorder) in 6–13 Year-Old Students: A Randomized, Double-Blind, Placebo-Controlled Study, European Journal of Integrative Medicine (2019)
29. The Influential Role of Parents’ Socioeconomic Status and Diet Quality on Their Children’S Dietary Behavior: Results From the Lipokap Study Among the Iranian Population, BMC Pediatrics (2023)
30. Exposure to Phthalates and Bisphenol a Is Associated With Higher Risk of Cardiometabolic Impairment in Normal Weight Children, Environmental Science and Pollution Research (2019)
31. Ultra-Processed Foods Intake in Relation to Metabolic Health Status, Serum Brain-Derived Neurotrophic Factor and Adropin Levels in Adults, Nutrition Journal (2024)
32. Dietary Polyphenols and the Risk of Metabolic Syndrome: A Systematic Review and Meta-Analysis, BMC Endocrine Disorders (2024)
33. Diet Quality Among Iranian Adolescents Needs Improvement, Public Health Nutrition (2015)
34. The Association of Dietary Choline and Betaine and Anthropometric Measurements Among Iranian Children: A Cross-Sectional Study, BMC Pediatrics (2021)
35. Is Dietary Vitamin B Intake Associated With Weight Disorders in Children and Adolescents? the Weight Disorders Survey of the Caspian-Iv Study, Health Promotion Perspectives (2019)
36. Longitudinal Association of Metabolic Syndrome and Dietary Patterns: A 13-Year Prospective Population-Based Cohort Study, Nutrition, Metabolism and Cardiovascular Diseases (2018)
37. The Association Between Dietary Habits and Metabolic Syndrome: Findings From the Shahedieh-Cohort Study, BMC Nutrition (2022)
38. Validity and Reproducibility of a Semi-Quantitative Food Frequency Questionnaire for Iranian Adults, Nutrition and Dietetics (2021)
39. Associations Between Empirically Derived Dietary Patterns and Oxidative Stress and Inflammation in Adults With Primary Hypothyroidism: A Case-Control Study, BMC Endocrine Disorders (2023)
40. Major Dietary Patterns Among Female Adolescent Girls of Talaat Intelligent Guidance School, Tabriz, Iran, Iranian Red Crescent Medical Journal (2012)
41. Investigation of Efficacy of Short-Acting Methylphenidate (Ritalin) and Long-Acting (Matoride) on Symptoms of Attention Deficit Hyperactivity Disorder in Children Aged 6–18 Years: A Single-Blind, Randomized Clinical Trial, Advanced Biomedical Research (2020)
42. The Effect of Vitamin D and Magnesium Supplementation on the Mental Health Status of Attention-Deficit Hyperactive Children: A Randomized Controlled Trial, BMC Pediatrics (2021)
43. Association of Dietary Phytochemical Index and Mental Health in Women: A Cross-Sectional Study, British Journal of Nutrition (2019)
44. Nutrition and Physical Activity in Iranian Dyslipidemic Patients, Acta Medica Iranica (2019)
45. Dietary Total Antioxidant Capacity in Relation to Depression and Anxiety in Iranian Adults, Nutrition (2019)
46. Snacking Behavior and Obesity Among Female Adolescents in Isfahan, Iran, Journal of the American College of Nutrition (2016)
47. The Relation Between Dietary Phytochemical Index and Metabolic Health Status in Overweight and Obese Adolescents, Scientific Reports (2023)
48. Association Between Junk Food Consumption and Mental Health in a National Sample of Iranian Children and Adolescents: The Caspian-Iv Study, Nutrition (2014)
49. Associations of Fruit and Vegetable Intake With Metabolic Health Status in Overweight and Obese Youth, Annals of Nutrition and Metabolism (2023)
50. Association of Dietary Fats With Ischemic Heart Disease (Ihd): A Case–Control Study, Journal of Health, Population and Nutrition (2024)