Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Efficacy of Permethrin-Impregnated Uniforms in the Prevention of Cutaneous Leishmaniasis in Iranian Soldiers



Sadeghnia A1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Department of Dermatology, St. Zahra Hospital, Isfahan Univ. of Medical Sciences, Isfahan, Iran

Source: Iranian Journal of Medical Sciences Published:2002

Abstract

Background: One approach for prevention of cutaneous leishmaniasis is creation of a barrier between the insect vector (phlebotomus) and the host. Many, but not all, researchers claim that permethrin-impregnated uniforms are effective for prevention of cutaneous leishmaniasis. We determined the efficacy of permethrin-impregnated uniforms for prevention of cutaneous leishmaniasis among Iranian soldiers. Methods: 324 soldiers were randomized into two equal groups. 272 soldiers completed the study. In Group A, 134 soldiers were issued permethrin impregnated uniforms. In Group B, 138 soldiers were issued uniforms washed in water. The soldiers wore uniforms day and night for 3 months, and were observed for an additional 6 months. All of the soldiers remained during this 3 months in the leishmaniasis-endemic area of Isfahan. Results: 9 (6.5%) of 138 soldiers wearing control uniforms and 6 (4.4%) of 134 soldiers wearing permethrin-impregnated uniforms acquired cutaneous leishmaniasis. The difference between the two groups was not statistically significant. Conclusion: Permethrin-impregnated uniforms may not be effective in prevention of cutaneous leishmaniasis.
Related Docs
View other Related Docs
1. Efficacy of Permethrin-Impregnated Uniforms in the Prevention of Cutaneous Leishmaniasis in Iranian Soldiers, Journal of Clinical Pharmacy and Therapeutics (2003)
2. Evaluation of the 11-Year Trend of Cutaneous Leishmaniasis in Six Main Foci of the Disease in Isfahan Province During the Years 2008 to 2018, Journal of Isfahan Medical School (2022)
3. Gis-Based Risk Mapping of Cutaneous Leishmaniasis: A Survey in an Endemic Area of Central Iran, Environmental Science and Pollution Research (2021)
4. Distribution Frequency of Pathogenic Bacteria Isolated From Cutaneus Leishmaniasis Lesions, Korean Journal of Parasitology (2008)
5. Treatment of Cutaneous Leishmaniasis With Aminosidine (Paromomycin) Ointment: Double-Blind, Randomized Trial in the Islamic Republic of Iran, Bulletin of the World Health Organization (2003)
6. Behaviors and Perceptions Related to Cutaneous Leishmaniasis in Endemic Areas of the World: A Review, Acta Tropica (2021)
7. Residential Environment, Human Behavior and Socio-Economic Status in Transmission of Cutaneous Leishmaniasis in Central Iran, Scientific Reports (2025)
8. Evaluation of the Biodiversity and Distribution of Sand Flies and Tracking of Leishmania Major in Them in Central Iran, International Journal of Environmental Health Research (2024)
Experts (# of related papers)
View all Related Experts
Seyed Hossein Hejazi (6)
Sedighe Saberi (4)
Other Related Docs
9. Efficacy of Integrated Pest Management in Controlling and Preventing Zoonotic Cutaneous Leishmaniasis in Isfahan Province, Iran, Journal of Isfahan Medical School (2012)
10. Evaluation of Community Interventions in Changes in Incidence of Cutaneous Leishmaniasis in Isfahan Province From 2002 to 2018: An Interrupted Time Series Regression Analysis, Iranian Journal of Epidemiology (2021)
11. Epidemiological Aspects of Cutaneous Leishmaniasis in Iran, Archives of Clinical Infectious Diseases (2015)
12. A Randomised, Double-Blind, Controlled Trial of a Killed L. Major Vaccine Plus Bcg Against Zoonotic Cutaneous Leishmaniasis in Iran, Vaccine (1999)
13. An Outbreak of Cutaneous Leishmaniasis Due to Leishmania Major in an Endemic Focus in Central Iran, Journal of Parasitic Diseases (2022)
14. The Skin Side Effects of Topical Glucantime in Patients With Cutaneous Leishmaniasis, Journal of Isfahan Medical School (2015)
15. Evaluation of Leishmanin Skin Test Reaction in Different Variants of Cutaneous Leishmaniasis, Indian Journal of Dermatology (2013)
16. Demographic and Clinical Characteristics of Children With Cutaneous Leishmaniasis in Isfahan Province, Iran, During 2011-2015, Journal of Isfahan Medical School (2017)
17. Evaluation of Leishmanin Skin Test and Its Relationship With the Clinical Form and Duration of Cutaneous Leishmaniasis, Dermatology Online Journal (2006)
18. Isolation of Bacteria Causing Secondary Bacterial Infection in the Lesions of Cutaneous Leishmaniasis, Indian Journal of Dermatology (2008)
19. Vaccination in Leishmaniasis: A Review Article, Iranian Biomedical Journal (2022)
20. Emergence of Cutaneous Leishmaniasis Due to Leishmania Major in a New Focus of Central Iran, Transactions of the Royal Society of Tropical Medicine and Hygiene (2009)
21. A New Focus of Zoonotic Cutaneous Leishmaniasis in Shiraz, Iran, Transactions of the Royal Society of Tropical Medicine and Hygiene (2009)
22. Immune Response Measured in Human Volunteers Vaccinated With Autoclaved Leishmania Major Vaccine Mixed With Low Dose of Bcg, Clinical and Experimental Immunology (2003)
23. Randomised Vaccine Trial of Single Dose of Killed Leishmania Major Plus Bcg Against Anthroponotic Cutaneous Leishmaniasis in Bam, Iran, Lancet (1998)
24. Comparison Between the Efficacy of Photodynamic Therapy and Topical Paromomycin in the Treatment of Old World Cutaneous Leishmaniasis: A Placebo-Controlled, Randomized Clinical Trial, Journal of Isfahan Medical School (2012)
25. Reevaluating Leishmanin Skin Test As a Marker for Immunity Against Cutaneous Leishmaniasis, International Journal of Dermatology (2013)
26. Comparative Study on the Effectiveness of Coumavec® and Zinc Phosphide in Controlling Zoonotic Cutaneous Leishmaniasis in a Hyperendemic Focus in Central Iran, Journal of Arthropod-Borne Diseases (2012)
27. Molecular Identification of Leishmania Species in Phlebotomus Alexandri (Diptera: Psychodidae) in Western Iran, Journal of Arthropod-Borne Diseases (2020)
28. Comparison Between the Efficacy of Photodynamic Therapy and Topical Paromomycin in the Treatment of Old World Cutaneous Leishmaniasis: A Placebo-Controlled, Randomized Clinical Trial, Indian Journal of Dermatology (2006)
29. The Epidemiology of Cutaneous Leishmaniasis in Isfahan Province, Iran, During 2001-2011, Journal of Isfahan Medical School (2015)
30. Cutaneous Leishmaniasis Based on Climate Regions in Iran (1998-2021): A Systematic Review and Meta-Analysis, Advanced Biomedical Research (2022)
31. Domestic and Peridomestic Risk Factors Associated With Transmission of Cutaneous Leishmaniasis in Three Hypo Endemic, Endemic, and Hyper Endemic Areas: A Randomized Epidemiological Study, Journal of Research in Medical Sciences (2014)
32. Cutaneous Leishmaniasis Reinfection: Skin Disease and Leishmaniasis Research Center, Isfahan, Iran, Journal of Isfahan Medical School (2015)
33. The Epidemiology of Cutaneous Leishmaniasis in Ardestan City, Iran, During the Years 2012 to 2019, Journal of Isfahan Medical School (2020)
34. Comparing the Effects of Topical Miltefosine and Glucantime in Treatment of Cutaneous Leishmaniasis, Journal of Isfahan Medical School (2014)
35. Study of Fauna, Activity Patterns and Leishmania Infection Rate of Phlebotomine Sand Flies in Western Iran, Journal of Parasitic Diseases (2021)
36. The Knowledge, Attitude, and Prevention Practices of Students Regarding Cutaneous Leishmaniasis in the Hyperendemic Region of the Shahid Babaie Airbase, Vector-Borne and Zoonotic Diseases (2012)
37. Epidemiology and Clinical Features of Cutaneous Leishmaniasis in Badrood City, Iran, in 2013, Journal of Isfahan Medical School (2015)