The Effect of Adding Fentanyl or Sufentanil to Intrathecal Marcaine on Sensory and Motor Block, Iintraoperative Hemodynamic Status and Pain Reduction After Lumbar Disc Surgery



Attari M^{1, 2} ; Khalili G^{1, 2} ; Saffari A³ Show Affiliations
Source: Journal of Isfahan Medical School Published:2016

Abstract

Background: This study aimed to investigate the properties of adding fentanyl or sufentanil to intrathecal Marcaine on sensory and motor block, intraoperative hemodynamic status and reducing of pain in patients after lumbar disc surgery and compare it with the control group. Methods: In a clinical-trial study, 96 patients undergoing lumbar disc surgery with spinal anesthesia were distributed in three groups of 32 people. Fentanyl and sufentanile were added to Marcaine in the first and second group, respectively, and in the third group, only Marcaine was injected. The severity of postoperative pain, the analgesic requirement and time of first receiving the drug and drug intake in the three groups were determined and compared during 24 hours after the surgery. Findings: During the stay of fentanyl, sufentanil and control groups in recovery, 40.6, 6.3 and 59.4 percent of the patients had pain in the groups, respectively, and there were significant differences among the three groups (P < 0.001). The severity of postoperative pain from 2 to 12 hours after the surgery was significant between the three groups (P = 0.010). Conclusion: The results of this study showed that using fentanyl or sufentanil with Marcaine led to reduced incidence and severity of postoperative pain after lumbar disc surgery and thus reduction in opioid usage. © 2016, Isfahan University of Medical Sciences(IUMS). All rights reserved.