Isfahan University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! On (X network) By
Mycobacterium Gordonae Pulmonary Infection With Clinical Manifestations Similar to Tuberculosis



Keikha M1 ; Khorshidi M1 ; Navid S1
Authors
Show Affiliations
Authors Affiliations
  1. 1. Student in Medical Microbiology, Isfahan Medical School, Isfahan, Iran

Source: Scientific Journal of Kurdistan University of Medical Sciences Published:2018

Abstract

Background and Aim: Mycobacterium gordonae is one of the most important human mycobacterial pathogens that is found in immuno-compromised patients and also healthy people. This study is the first case report of Mycobacterium gordonae infection from Iran. Material and Methods: A 39-year-old woman with fever, weight loss, anorexia, chest pain and persistent cough referred to the emergency department of Al-Zahra Hospital in Isfahan,. A sputum sample was taken from the patient. After eleven days bacterial colonies were observed on the Lowenstein–Jensen Medium. Using microscopic evaluation and biochemical tests, the bacterial colonies were identified as Mycobacterium gordonae. Considering the antibiotic resistance pattern clarithromycin and levofloxacin, were prescribed for the patient. The patient's clinical signs were improved after 6 weeks. Conclusion: The clinical and radiological manifestations of mycobacterium gordonae and tuberculosis are similar and may be mistaken for each other. In addition, therapeutic regimen for non-tuberculosis mycobacteria and tuberculosis are different. Therefore it is necessary to identify mycobacteria to the species level. © 2018, Kurdistan University of Medical Sciences. All rights reserved.
Related Docs
View other Related Docs
1. Mycobacteriosis and Tuberculosis: Laboratory Diagnosis, Open Microbiology Journal (2018)
2. Misleading of the Diagnosis of Mycobacterium Attributed Lung Diseases to Malignancy Due to Smear, Culture and Pcr Negative Results: A Lesson From a Case Report, Indian Journal of Tuberculosis (2020)
3. Rapid and Accurate Identification of Mycobacterium Tuberculosis Complex and Common Non-Tuberculous Mycobacteria by Multiplex Real-Time Pcr Targeting Different Housekeeping Genes, Current Microbiology (2012)
4. Species Identification of Neglected Nontuberculous Mycobacteria in a Developing Country, Japanese Journal of Infectious Diseases (2011)
5. The Case Report of Mycobacterium Arupense Wound Infection in Diabetes Mellitus Patients; the First Report and Literature Review, Access Microbiology (2020)
6. Drug Resistance Pattern of Mycobacterium Tuberculosis Isolates From Patients of Five Provinces of Iran, Asian Pacific Journal of Tropical Medicine (2014)
7. Identification of Nontuberculous Mycobacteria Species Isolated From Water Samples Using Phenotypic and Molecular Methods and Determination of Their Antibiotic Resistance Patterns by E- Test Method, in Isfahan, Iran, Iranian Journal of Basic Medical Sciences (2012)
8. Molecular Microbiological Investigation of Post-Vaccination Bacille Calmette-Guerin Infection in Iranian Patients, International Journal of Tuberculosis and Lung Disease (2011)
Experts (# of related papers)
View all Related Experts
Hasan Shojaei (18)
Bahram Nasr Esfahani (12)
Other Related Docs
9. Identification of Non-Tuberculosis Mycobacteria Isolates by Polymerase Chain Reaction-Restriction Enzyme Analysis of 360-Bp Fragment of Rpob Gene, Journal of Isfahan Medical School (2014)
10. First Report on Isolation and Molecular Characterization of Clinical Mycobacterium Setense Isolates in Asia, Japanese Journal of Infectious Diseases (2011)
11. Prevalence and Molecular Characterization of Non-Tuberculous Mycobacteria in Hospital Soil and Dust of a Developing Country, Iran, Microbiology (United Kingdom) (2019)
12. Urinary Polymerase Chain Reaction for Diagnosis of Urogenital Tuberculosis., Urology journal (2008)
13. The Role of Urine Polymerase Chain Reaction Test in Diagnosis of Genitourinary Tuberculosis, Journal of Isfahan Medical School (2007)
14. Evaluation of the Changes in Tuberculin Skin Test (Tst) Among the Interns in Isfahan University of Medical Sciences (Iums), Iran, After One Year of Starting Internship During the Years 2016-2017, Journal of Isfahan Medical School (2018)
15. Identification and Molecular Characterization of Mycobacteria Isolated From Animal Sources in a Developing Country, Acta Tropica (2020)
16. Molecular Characterization of Environmental Non-Tuberculous Mycobacteria Using Pcr- Rflp Analysis of 441 Bp Heat Shock Protein 65 Fragments, Iranian Journal of Public Health (2012)
17. Evaluation of Cellular Immunogenicity of Recombinant Cytochrome P450 Cyp141 Protein of Mycobacterium Tuberculosis in Human and Mouse Model, Biologicals (2018)
18. First Case Report of Pulmonary and Cutaneous Nocardiosis Caused by Nocardia Mexicana in Iran, Access Microbiology (2019)
19. Impaired Il-12- and Il-23-Mediated Immunity Due to Il-12Rβ1 Deficiency in Iranian Patients With Mendelian Susceptibility to Mycobacterial Disease, Journal of Clinical Immunology (2018)
20. Study of the Tuberculous Infection Rate and Presence of Atypical Mycobacterium Infection in Schoolchildren in Isfahan, Iran, Journal of Tropical Pediatrics (1980)
21. Cloning of the Recombinant Cytochrome P450 Cyp141 Protein of Mycobacterium Tuberculosis As a Diagnostic Target and Vaccine Candidate, Iranian Red Crescent Medical Journal (2014)
22. Sequence-Based Detection of First-Line and Second-Line Drugs Resistance-Associated Mutations in Mycobacterium Tuberculosis Isolates in Isfahan, Iran, Infection, Genetics and Evolution (2020)
23. First Report of Isolation of Mycobacterium Novocastrense From Water Supplies, APMIS (2014)
24. First Report of Isolation of Mycobacterium Canariasense From Hospital Water Supplies, Scandinavian Journal of Infectious Diseases (2014)
25. Resistance to First-Line Drugs in Clinical Isolates of Mycobacterium Tuberculosis in Isfahan, Journal of Isfahan Medical School (2022)
26. Species Diversity and Molecular Characterization of Nontuberculous Mycobacteria in Hospital Water System of a Developing Country, Iran, Microbial Pathogenesis (2016)
27. Direct Drug Susceptibility Testing of Mycobacterium Tuberculosis Using the Proportional Method: A Multicenter Study, Journal of Global Antimicrobial Resistance (2019)
28. Ethambutol-Susceptibility of Clinical and Environmental Atypical Mycobacteria Isolated From Isfahan, Iran, Journal of Isfahan Medical School (2013)
29. Report of Two Cases of Mycobacterium Europaeum From Iran, Japanese Journal of Infectious Diseases (2012)
30. Expression and Purification of the Recombinant Cytochrome P450 Cyp141 Protein of Mycobacterium Tuberculosis As a Diagnostic Tool and Vaccine Production, Iranian Red Crescent Medical Journal (2015)
31. Mycobacterium Arupense Infection in Hiv-Infected Patients From Iran, International Journal of STD and AIDS (2013)
32. Antineutrophil Cytoplasmic Antibodies in Patients With Pulmonary Tuberculosis, Iranian Journal of Immunology (2011)
33. Molecular Identification of Rare Clinical Mycobacteria by Application of 16S-23S Spacer Region Sequencing, Iranian Journal of Basic Medical Sciences (2012)
34. Genetic Lineages of Mycobacterium Tuberculosis Isolates in Isfahan, Iran, Current Microbiology (2017)
35. Isolation of Nontuberculous Mycobacteria Existing in Isfahan (Iran) Hospital Water Supplies by Phenotypic Method, Journal of Isfahan Medical School (2013)
36. Chronic Pulmonary Disease Due to Mycobacterium Monacense Infection: The First Case From Iran, Annals of Laboratory Medicine (2012)
37. Immunophenotypic Characterization of Peripheral Blood T-Lymphocytes and Their Subpopulations in Tuberculosis Patients Before and After Treatments, Iranian Journal of Allergy, Asthma and Immunology (2005)
38. Genetic Diversity of Iranian Clinical Isolates of Mycobacterium Tuberculosis, New Microbiologica (2012)
39. Determination of Nontuberculosis Mycobacteria Species Genotypes Present in Cattle Milk Samples Using 16S Rrna Gene Direct Sequencing, Journal of Isfahan Medical School (2016)
40. Analysis of Dna Gyra Gene Mutation in Clinical and Environmental Ciprofloxacin-Resistant Isolates of Non-Tuberculous Mycobacteria Using Molecular Methods, Jundishapur Journal of Microbiology (2016)
41. Evaluating the Frequency of Resistance to Pyrazinamide Among Drug-Resistant Strains of Mycobacterium Tuberculosis in Isfahan, Iran, Archives of Clinical Infectious Diseases (2021)
42. Mycobacterium Iranicum Sp. Nov., a Rapidly Growing Scotochromogenic Species Isolated From Clinical Specimens on Three Different Continents, International Journal of Systematic and Evolutionary Microbiology (2013)
43. Screening, Isolation and Molecular Identification of Biodegrading Mycobacteria From Iranian Ecosystems and Analysis of Their Biodegradation Activity, AMB Express (2017)
44. Phylogenetic Analysis of Prevalent Tuberculosis and Non-Tuberculosis Mycobacteria in Isfahan, Iran, Based on a 360 Bp Sequence of the Rpob Gene, Jundishapur Journal of Microbiology (2016)