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Potential of [99Mtc] Tc-Ionps in Spect: A Systematic Review on Efficiency and Accumulation Rates Publisher



Garshad J1 ; Salarvand A1 ; Tavakoli M1, 2 ; Mansourian M1
Authors
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Authors Affiliations
  1. 1. Department of Medical Physics, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Department of General Medicine, School of Medicine, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Journal of Radioanalytical and Nuclear Chemistry Published:2024


Abstract

The aim of this study is to compare the efficiency and accumulation of 99mTc attached to iron oxide nanoparticles (IONPs) for use in the SPECT imaging. A comprehensive literature search identified 13 relevant studies, and the maximum absorbed dose per gram (ID/g) of [99mTc] Tc-IONPs in various organs at different time intervals was analyzed. The findings showed the distribution patterns of the compounds in each organ, emphasizing the significance of coating and nanoparticle size for optimal imaging results. By selecting the appropriate coating and nanoparticle size, imaging quality and accuracy can be improved. © Akademiai Kiado, Budapest, Hungary 2024.
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