Pathologic Findings in Sinonasal Polyposis and Predisposing Factors



Balouchi M¹ ; Berjis N¹ ; Okhovvat A¹ ; Abbasi H¹ ; Talebi S¹ Show Affiliations
Source: Journal of Isfahan Medical School Published:2007

Abstract

Background: The aim of this study was to evaluate the pathologic findings in patients with sinonasal polyposis after functional endoscopic sinus surgery, and to assess the relationship between these findings and the predisposing factors of polyposis. Methods: This prospective study was conducted from March 2004 to November 2006 among 30 patients. All patients underwent endoscopic sinus surgery after a detailed history and physical examination. The biopsy specimen was evaluated in two groups of eosinophilic and neutrophilic polyposis; then pathologic findings were compared with other findings. Findings: Overall, 20 patients (66.67%) were male and 10 (23.33%) were female. The highest frequency was seen in the 50-60-year age group. Allergic rhinitis and septal deviation were the most co-existing conditions. Eosinophilic polyposis was more prevalent than neutrophilic polyposis (18% vs. 12%, respectively, p=0. 04). Conclusion: Eosinophilic polyposis was more common than neutrophilic type. Males are more frequently affected than females. Allergic diseases and nasal structural abnormalities were the most important factors associated with nasal polyposis. © 2017, Isfahan University of Medical Sciences(IUMS). All rights reserved.