Evaluation of the Relationship Between the Severity of Generalized Edema in Patients Connected to the Ventilator With Mortality and Morbidity During Hospitalization in the Icu of Amin Hospital; [بررسی ارتباط بین شدت ادم جنرالیزه بیمارا ن متصل به ون تیلاتور با مورتالیتی طی زمان بست ری در Icu بیمارستان امین] Publisher



Mahjobipoor H ; Mortazavi M ; Nazemroaya B ; Jafari F
Source: Journal of Isfahan Medical School Published:2025

Abstract

Background: Patients hospitalized in the ICU are at high risk of developing edema due to Methods: This Findings: Conclusion: The certain conditions such as immobility, mechanical ventilation, low serum albumin, kidney disease, and heart failure. The study was conducted with the aim of investigating the effect of Alb, Na, BUN/Cr, and I/O levels on the severity of edema and the effect of edema severity on mortality and duration of hospitalization in the ICU. descriptive-analytical cross-sectional study was conducted on 1000 patients admitted to the ICU of Amin Hospital in Isfahan between 2015 and 2019. Patients over 16 years of age with generalized edema were included in the study. The levels of Na, Alb, Cr, BUN and I/O and the severity of edema of the patients were measured. Also, SOFA and APACHE II scores were used to match the confounders. Data were analyzed using multiple logistic regression. It was shown that the severity of edema affects mortality, although no correlation was observed between the duration of hospitalization in the ICU and the severity of edema. Multiple logistic regression showed that BUN level and BUN, Na, and I/O levels, respectively, after equalization based on APACHE II and SOFA, affect the severity of edema in patients hospitalized in the ICU. It was also shown that after equalization based on APACHE II, Alb and BUN levels, and after equalization based on SOFA, Na, Alb, and BUN levels affect the severity of edema in intubated patients. severity of peripheral edema affects the mortality of patients admitted to the ICU and intubated patients, highlighting the importance of edema management in these populations. Physicians should pay special attention to fluid management strategies. © 2025, Isfahan University of Medical Sciences(IUMS). All rights reserved.