Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy

Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy Publisher Pubmed

Beheshti M¹ ; Rabiei N² ; Taghizadieh M³ ; Eskandari P⁴ ; Mollazadeh S⁵ ; Dadgostar E^{6, 7} ; Hamblin MR⁸ ; Salmaninejad A^{9, 10} ; Emadi R¹¹ ; Mohammadi AH¹² ; Mirazei H¹²

Show Affiliations

1. Pathophysiology Laboratory, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
2. School of Medicine, Shiraz University of Medical Sciences, Shiraz, Iran
3. Department of Pathology, School of Medicine, Center for Women's Health Research Zahra, Tabriz University of Medical Sciences, Tabriz, Iran
4. Department of Biology, School of Basic Sciences, University of Guilan, Rasht, Iran
5. Natural Products and Medicinal Plants Research Center, North Khorasan University of Medical Sciences, Bojnurd, Iran
6. Behavioral Sciences Research Center, Isfahan University of Medical Sciences, Isfahan, Iran
7. Student Research Committee, Isfahan University of Medical Sciences, Isfahan, Iran
8. Laser Research Centre, Faculty of Health Science, University of Johannesburg, Doornfontein, 2028, South Africa
9. Regenerative Medicine, Organ Procurement and Transplantation Multi Disciplinary Center, Razi Hospital, School of Medicine, Guilan University of Medical Sciences, Rasht, Iran
10. Department of Medical Genetics, Faculty of Medicine, Tabriz University of Medical Sciences, Tabriz, Iran
11. School of Medicine, Kashan University of Medical Sciences, Kashan, Iran
12. Research Center for Biochemistry and Nutrition in Metabolic Diseases, Institute for Basic Sciences, Kashan University of Medical Sciences, Kashan, Iran

Source: Journal of Psychiatric Research Published:2023

Abstract

Obsessive-compulsive disorder (OCD) is a debilitating neuropsychiatric disorder, in which the patient endures intrusive thoughts or is compelled to perform repetitive or ritualized actions. Many cases of OCD are considered to be familial or heritable in nature. It has been shown that a variety of internal and external risk factors are involved in the pathogenesis of OCD. Among the internal factors, genetic modifications play a critical role in the pathophysiological process. Despite many investigations performed to determine the candidate genes, the precise genetic factors involved in the disease remain largely undetermined. The present review summarizes the single nucleotide polymorphisms that have been proposed to be associated with OCD symptoms, early onset disease, neuroimaging results, and response to therapy. This information could help us to draw connections between genetics and OCD symptoms, better characterize OCD in individual patients, understand OCD prognosis, and design more targeted personalized treatment approaches. © 2022 Elsevier Ltd

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Style	Citing Format
MLA	Beheshti M, et al.. "Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy." Journal of Psychiatric Research, vol. 157, no. , 2023, pp. 223-238.
APA	Beheshti M, Rabiei N, Taghizadieh M, Eskandari P, Mollazadeh S, Dadgostar E, Hamblin MR, Salmaninejad A, Emadi R, Mohammadi AH, Mirazei H (2023). Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy. Journal of Psychiatric Research, 157(), 223-238.
Chicago	Beheshti M, Rabiei N, Taghizadieh M, Eskandari P, Mollazadeh S, Dadgostar E, Hamblin MR, et al.. "Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy." Journal of Psychiatric Research 157, no. (2023): 223-238.
Harvard	Beheshti M et al. (2023) 'Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy', Journal of Psychiatric Research, 157(), pp. 223-238.
Vancouver	Beheshti M, Rabiei N, Taghizadieh M, Eskandari P, Mollazadeh S, Dadgostar E, et al.. Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy. Journal of Psychiatric Research. 2023;157():223-238.
BibTex	@article{ author = {Beheshti M and Rabiei N and Taghizadieh M and Eskandari P and Mollazadeh S and Dadgostar E and Hamblin MR and Salmaninejad A and Emadi R and Mohammadi AH and Mirazei H}, title = {Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy}, journal = {Journal of Psychiatric Research}, volume = {157}, number = {}, pages = {223-238}, year = {2023} }
RIS	TY - JOUR AU - Beheshti M AU - Rabiei N AU - Taghizadieh M AU - Eskandari P AU - Mollazadeh S AU - Dadgostar E AU - Hamblin MR AU - Salmaninejad A AU - Emadi R AU - Mohammadi AH AU - Mirazei H TI - Correlations Between Single Nucleotide Polymorphisms in Obsessive-Compulsive Disorder With the Clinical Features or Response to Therapy JO - Journal of Psychiatric Research VL - 157 IS - SP - 223 EP - 238 PY - 2023 ER -

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