The Effect of Intralesional Triamcinolone Versus Combination of Intralesional Triamcinolone With Co2 Fraxel Laser in Treatment of Patients With Hypertrophic Scars



Nilforoushzadeh MA¹ ; Siadat AH² ; Haftbaradaran E³ ; Shahbazi F⁴
Source: Journal of Isfahan Medical School Published:2013

Abstract

Background: Hypertrophic scars are benign growths of dermal collagen that can couse physical and psychological (cosmetic) problems for patients. Methods: A total of 36 patients were studied and randomly divided into 2 groups; 18 patients were treared with intralesional injection of triamcinolone and 18 other patients were treated with combination of fractional laser and intralesional injection of triamcinolone. The cure rate of the lesions in pain, induration, pruritus, erythema and burning were assessed and compared between the groups. Findings: In group with intralesional injection of triamcinolone, cure rate was 39% in erythema, 45% in pain, 100% in burning, 67% in induration and 45% in pruritus. In group with combination of fractional laser and intralesional injection of triamcinolone, cur was 89% in erythema, 67% in pain, 23% in burning, 83% in induration and 72% in pruritus. The differences between the groups were significant in all issues (P < 0.001 for all). Conclusion: This study showed that combination of fractional laser and intralesional injection of triamcinolone has significantly higher cure rate of hypertrophic scars than intralesional injection of triamcinolone alone.