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Maternal Asthma; Pregnancy, Delivery and Birth Outcomes: A Retrospective Cohort Study Pubmed



Vaezi A1 ; Haghighi L2 ; Beigmohammadi F3 ; Nojomi M4
Authors
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Authors Affiliations
  1. 1. Department of Community Medicine, School of Medicine, Medical University of Isfahan, Isfahan, Iran
  2. 2. Department of Obstetrics and Gynecology, Akbar-Abadi Hospital, Iran University of Medical Sciences, Iran
  3. 3. Department of Community Medicine, Iran University of Medical Sciences Tehran, Iran
  4. 4. Department of Community Medicine, Preventive Medicine and Public Health Research Center, Iran University of Medical Sciences, Tehran, 15875-6171, Iran

Source: Iranian Journal of Allergy, Asthma and Immunology Published:2017


Abstract

The aim of current study was to determine womens maternal asthma in pregnancy, delivery and birth outcomes. Using a retrospective cohort design, data of 580 pregnant women were gathered form a large teaching hospital in Tehran, Iran. The medical records of pregnant women who had attended this hospital between 2009 and 2011 were assessed. Data of delivery and birth outcomes were gathered by observation and medical records of women. Multiple logistic regression and adjusted odds ratio (OR) were used to assess the independent association of asthma and outcomes. 274 patients (47.2%) were in asthmatic group and 306 patients (52.8%) were in the non-Asthmatic group. Basic and demographic variables showed the same distribution across two groups. Maternal asthma showed an adjusted relationship with gestational diabetes (OR=2.64), gestational hypertension (OR=3.79), cesarean delivery (OR=2.68), small for gestational age (OR=2.86), premature rupture of membrane (OR=2.18), preterm delivery (OR=1.74), abnormal vaginal bleeding (OR=3.75), and low birth weight (OR=1.78) significantly (p<0.05 for all associations). The majority of pregnancy, delivery and birth outcomes except fetal death, abortion, placenta previa and placenta abruption) were significantly associated with maternal asthma. The largest association of maternal asthma was with gestational hypertension and abnormal vaginal bleeding respectively. Copyright © Spring 2017, Iran J Allergy Asthma Immunol. All rights reserved.
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