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Association of Lymphovascular Space Invasion (Lvsi) With Histological Tumor Grade and Myometrial Invasion in Endometrial Carcinoma: A Review Study Publisher

Summary: LVSI linked to poorer prognosis in endometrial carcinoma, highlighting its significance. Research shows high LVSI correlates with advanced tumor grade. Are more studies needed? #EndometrialCancer #PrognosticFactors

Rafiee A ; Mohammadizadeh F
Authors

Source: Advanced Biomedical Research Published:2023


Abstract

Endometrial carcinoma is one of the most frequent gynecological cancers in developed countries. Lymphovascular space invasion (LVSI), histological grade, and myometrial invasion (MMI) are important prognostic factors of endometrial carcinoma. LVSI is considered an independent poor prognostic factor in endometrial carcinoma. Based on the importance of LVSI, this study aimed to discuss the association of LVSI with tumor grade and MMI. A search of PubMed, EMBASE, Web of Science, Scopus, Google Scholar, and Cochrane Library was carried out to collect related studies. Consequently, most studies showed that LVSI is significantly associated with higher histologic grade and deep MMI. © 2023 Elsevier B.V., All rights reserved.
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