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Cytomegalovirus Colitis in a 10 Year-Old Girl After Kidney Transplantation



Merrikhi AR2 ; Amirshahkarami SM1 ; Saneian H1
Authors
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Authors Affiliations
  1. 1. Department of Pediatrics, Isfahan University of Medical Sciences, Isfahan, Iran
  2. 2. Kidney Disease Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Iranian Journal of Pediatrics Published:2013

Abstract

Background: Cytomegalovirus is an important infection in kidney Transplantation. Isolation of the CMV virus or detection of its proteins or nucleic acid in any body fluid or tissue specimen is defined as CMV infection. Case Presentation: A 10-year-old girl was admitted frequently for vomiting and colicky watery diarrhea starting one month after renal transplantation from a non-relative living donor. Cr, BUN, serum electrolytes and also liver function tests were normal. Anti CMV IgM titer was negative before and after transplantation. On colonoscopy large aphthous like lesions were detected in the colon. CMV PCR of the lesion was strongly positive (>2000 copies/ml). The patient received Ganciclovir. Conclusion: Usually CMV infected patients present with renal dysfunction after renal transplantation but other organ involvements must not be ignored. We report a patient presenting only with intestinal signs and symptoms of CMV infection. © 2013 by Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, All rights reserved.
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