Sudden Death Following Suicide With Colchicine and Chloroquine

Sudden Death Following Suicide With Colchicine and Chloroquine Publisher

Dorooshi G¹ ; Zoofaghari S¹ ; Samsamshariat S¹ ; Rahimi A² ; Otroshi A¹

Show Affiliations

1. Department of Clinical Toxicology, Isfahan Clinical Toxicology Research Center, Khorshid Hospital, Isfahan University of Medical Sciences, Isfahan, Iran
2. Clinical Informationist Research Group, Health Information Research Center, Isfahan University of Medical Sciences, Isfahan, Iran

Source: Advanced Biomedical Research Published:2020

Abstract

Poisoning with any of the colchicine or chloroquine drugs is rare. These drugs exert therapeutic and toxic effects on tissues by different mechanisms. Colchicine is used to treat a number of rheumatologic diseases and heart problems. In addition, chloroquine is used to treat malaria and some inflammatory diseases. There is a small gap between the therapeutic and toxic doses of these drugs. Gastrointestinal symptoms are the initial causes of poisoning with these drugs and then widespread organ failure in later stages can lead to sudden cardiac death. We introduce a case of concurrent poisoning with both drugs, in which the patient presented with a headache, nausea, and vomiting several hours after suicide. On the 1st day, the patient’s status was stable, but on the 2nd day, the patient suddenly becomes ill and died even though the patient received supportive therapy. Concurrent poisoning with chloroquine and colchicine is extremely lethal, and early aggressive management is recommended even in an apparently stable patient. © 2020 Advanced Biomedical Research | Published by Wolters Kluwer - Medknow.

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Style	Citing Format
MLA	Dorooshi G, et al.. "Sudden Death Following Suicide With Colchicine and Chloroquine." Advanced Biomedical Research, vol. 9, no. 1, 2020, pp. 40-.
APA	Dorooshi G, Zoofaghari S, Samsamshariat S, Rahimi A, Otroshi A (2020). Sudden Death Following Suicide With Colchicine and Chloroquine. Advanced Biomedical Research, 9(1), 40-.
Chicago	Dorooshi G, Zoofaghari S, Samsamshariat S, Rahimi A, Otroshi A. "Sudden Death Following Suicide With Colchicine and Chloroquine." Advanced Biomedical Research 9, no. 1 (2020): 40-.
Harvard	Dorooshi G et al. (2020) 'Sudden Death Following Suicide With Colchicine and Chloroquine', Advanced Biomedical Research, 9(1), pp. 40-.
Vancouver	Dorooshi G, Zoofaghari S, Samsamshariat S, Rahimi A, Otroshi A. Sudden Death Following Suicide With Colchicine and Chloroquine. Advanced Biomedical Research. 2020;9(1):40-.
BibTex	@article{ author = {Dorooshi G and Zoofaghari S and Samsamshariat S and Rahimi A and Otroshi A}, title = {Sudden Death Following Suicide With Colchicine and Chloroquine}, journal = {Advanced Biomedical Research}, volume = {9}, number = {1}, pages = {40-}, year = {2020} }
RIS	TY - JOUR AU - Dorooshi G AU - Zoofaghari S AU - Samsamshariat S AU - Rahimi A AU - Otroshi A TI - Sudden Death Following Suicide With Colchicine and Chloroquine JO - Advanced Biomedical Research VL - 9 IS - 1 SP - 40 EP - PY - 2020 ER -

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