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Right Ventricle Tumoral Mass in Acute Promyelocytic Leukemia (Aml M3): Cardiac Magnetic Resonance Findings



Nikdoust F1 ; Sani ZA2 ; Tabatabaei SA1
Authors
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Authors Affiliations
  1. 1. Department of Cardiology, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of MRI, Shahid Rajaie Cardiovascular, Medical, and Research Center, Iran University of Medical Sciences, Tehran, Iran

Source: Iranian Heart Journal Published:2016

Abstract

Intracardiac masses found on 2D echocardiography in patients with leukemia can present diagnostic challenges. A correct differentiation between thrombi, metastases, and infective vegetations is important in the management of patients with leukemia. We describe a 24-year-old male patient, who was diagnosed with acute myelogenous leukemia (APL, AML M3). 2D transthoracic echocardiography showed 2 inhomogeneous highly mobile masses (10×13 and 6×9 mm) in the right ventricle (RV). The masses were attached to the chordae tendineae and exhibited movements compatible with the cardiac cycle. Cardiac magnetic resonance imaging revealed 3 mobile masses in the RV attached to the RV trabeculations with isosignal intensity on steady-state free precession sequence. There was no obvious evidence of mass invasion or necrosis. On the last transesophageal echocardiography (6 months after the initial admission), the mass did not exist anymore. At the time of paper compilation, the patient has no complaints and is in remission. This report underscores the importance of cardiac magnetic resonance imaging in differentiating intracardiac thrombi from aggregations of tumoral cells in APL, AML M3. © 2016, Iranian Heart Association. All rights reserved.