The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates

The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates Publisher

Alaei M¹ ; Rohani F² ; Norouzi E³ ; Hematian Boroujeni N³ ; Tafreshi RI⁴ ; Salehiniya H⁵ ; Soheilipour F⁶

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1. Department of Pediatric Endocrinology and Metabolism, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
2. Pediatric Growth and Development Research Center, Institute of Endocrinology and Metabolism, Iran University of Medical Science, Tehran, Iran
3. Department of Pediatrics, Iran University of Medical Sciences, Tehran, Iran
4. Department of Pediatrics, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
5. Social Determinants of Health Research Center, Birjand University of Medical Sciences, Birjand, Iran
6. Minimally Invasive Surgery Research Center, Iran University of Medical Sciences, Tehran, Iran

Source: Frontiers in Endocrinology Published:2020

Abstract

Background and Objectives: Clitoromegaly is an important parameter in the evaluation of ambiguous genitalia in neonates, but the normative data for clitoral size in newborns have racial/ethnic differences. The present study aimed to determine clitoral length (CL) and clitoral width (CW) values and establish cutoff measurement to define clitoromegaly in both term and preterm Iranian neonates for the first time. Methods: A total number of 580 female newborn infants delivered at 28–42 weeks of gestation were enrolled in the study, and their CL and CW were measured on the first 72 h of birth. Data about birth weight (BW), body length (BL), and head circumference (HC) of newborns; mothers' age; and gestational age (GA) were recorded, too. Results were presented as mean ± standard deviation (SD) for quantitative variables and were summarized by frequency (percentage) for categorical variables. Backward stepwise regression analysis was used for prediction of CL and CW. Results: Among 580 Iranian female newborns studied, 187 were term neonates and the other 393 newborns were preterm. Mean ± SD values of CL were 6.11 ± 0.39 mm in term infants and 5.45 ± 0.64 mm in preterm infants (P < 0.001). Mean ± SD values of CW were 4.22 ± 0.43 in term infants and 3.68 ± 0.53 in preterm infants (P < 0.001). Regression analysis showed that CL was correlated with GA considered by last menstrual period, BL, BW, and HC; and CW was associated with GA, BL, and BW. Conclusion: This study suggests normative values (mean + 1, 2, and 3 SD) of CL and CW according to GA, which can be used as a reference for Middle East's newborns, especially Iranian newborn babies. © Copyright © 2020 Alaei, Rohani, Norouzi, Hematian Boroujeni, Tafreshi, Salehiniya and Soheilipour.

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1. The Nomogram of Penile Length and Circumference in Iranian Term and Preterm Neonates, Frontiers in Endocrinology (2018)

Style	Citing Format
MLA	Alaei M, et al.. "The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates." Frontiers in Endocrinology, vol. 11, no. , 2020, pp. -.
APA	Alaei M, Rohani F, Norouzi E, Hematian Boroujeni N, Tafreshi RI, Salehiniya H, Soheilipour F (2020). The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates. Frontiers in Endocrinology, 11(), -.
Chicago	Alaei M, Rohani F, Norouzi E, Hematian Boroujeni N, Tafreshi RI, Salehiniya H, Soheilipour F. "The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates." Frontiers in Endocrinology 11, no. (2020): -.
Harvard	Alaei M et al. (2020) 'The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates', Frontiers in Endocrinology, 11(), pp. -.
Vancouver	Alaei M, Rohani F, Norouzi E, Hematian Boroujeni N, Tafreshi RI, Salehiniya H, et al.. The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates. Frontiers in Endocrinology. 2020;11():-.
BibTex	@article{ author = {Alaei M and Rohani F and Norouzi E and Hematian Boroujeni N and Tafreshi RI and Salehiniya H and Soheilipour F}, title = {The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates}, journal = {Frontiers in Endocrinology}, volume = {11}, number = {}, pages = {-}, year = {2020} }
RIS	TY - JOUR AU - Alaei M AU - Rohani F AU - Norouzi E AU - Hematian Boroujeni N AU - Tafreshi RI AU - Salehiniya H AU - Soheilipour F TI - The Nomogram of Clitoral Length and Width in Iranian Term and Preterm Neonates JO - Frontiers in Endocrinology VL - 11 IS - SP - EP - PY - 2020 ER -

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