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Role of Kobayashi Risk Scoring for Determining Refractory Kawasaki Disease Publisher



Raeeskarami SR1 ; Tahghighi F1 ; Bigdeli AHZ1 ; Assari R3 ; Ziaee V1, 4 ; Aghighi Y1, 4 ; Sadeghi P1, 5
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Authors Affiliations
  1. 1. Pediatric Rheumatology Research Group, Rheumatology Research Center, Bahrami Children's Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Bahrami Children's Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Vali-Asr Hospital, Imam Khomeini Complex, Tehran University of Medical Science, Tehran, Iran
  4. 4. Pediatrics Center of Excellence, Children's Medical Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Pediatrics, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Journal of Comprehensive Pediatrics Published:2018


Abstract

Background: Coronary complications are common in children with Kawasaki disease (KD). Administration of intravenous immunoglobulin (IVIG) during the first 10 days will result in lower coronary complications. It is useful to predict if a patient will develop coronary complications or not. Objectives: We designed this study to evaluate the role of Kobayashi risk scoring for determining refractory KD. Methods: Medical records of all cases withKDwere reviewed and demographic data, previous history, coronary arteryinvolvement, laboratory findings, and days with fever were extracted for all cases. Kobayashi score was calculated. Results: A total of 168 cases enrolled. There was no significant difference regarding Kobayashi score in different groups regarding coronary involvement. Incases without coronary involvement, 93.5% were classifiedas low risk, in one and two vessels involvement groups, all were categorized as low risk, and among three vessels involvement cases, 75% were known as low risk. Conclusions: Kobayashi score is not useful for predicting severity of coronary involvement in Kawasaki disease. Copyright © 2018, Journal of Comprehensive Pediatrics.
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