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Ovarian Adenosarcoma in a Postmenopausal Woman: Case Report and Review of Literature Publisher



Mousavi AS1 ; Zamani N1 ; Mohseni M2 ; Zamani F3 ; Mehr SGD4 ; Sarmadi S5
Authors
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Authors Affiliations
  1. 1. Department of Gynecologic Oncology, Vali-Asr Hospital, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Obstetrics and Gynecology, Women's Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of Radiology, Children Medical Center of Excellence, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Obstetrics and Gynecology, School of Medicine, Urmia University of Medical Sciences, Urmia, Iran
  5. 5. Pathology, Tehran University of Medical Sciences, Tehran, Iran

Source: International Journal of Surgery Case Reports Published:2023


Abstract

Introduction and importance: Mullerian adenosarcoma is a rare malignancy that generally occurs in the uterine corpus but uncommonly, it may be found extrauterine. Ovarian adenosarcoma is extremely rare and often is presented in reproductive age women. Most of them are low grade and have a good prognosis except for adenosarcoma with sarcomatous overgrowth. Case presentation: A 77-year-old menopausal woman presented with abdominal discomfort. She had severe ascites and elevated levels of CA-125, CA 19-9, and HE4 tumor markers. Adenosarcoma with sarcomatous overgrowth was diagnosed after the histopathological examination of the surgical biopsy. Conclusion: The possibility of endometriosis transformation to malignancy even in postmenopausal women may warrant continuous follow-up for early diagnosis of ovarian cancer, this potentially fatal disease. More studies are needed to find the best therapeutic approach to adenosarcoma with sarcomatous overgrowth. © 2023 The Authors