Incidence and Risk Factors for Post-Intravitreal Injection Endophthalmitis in a Modified Operating Room Setting Publisher Pubmed



Zarei M¹ ; Karkhaneh R¹ ; Mahmoudzadeh R¹ ; Salabati M¹ ; Nabavi A¹ ; Yaseri M² ; Najibzadeh E¹ ; Roohipoor R¹ ; Riazi Esfahani M¹ ; Khodabande A¹ ; Ghassemi F¹ ; Ebrahimiadib N¹ ; Khojasteh H¹ ; Modjtahedi BS^{3, 4}
Source: Ocular Immunology and Inflammation Published:2019

Abstract

Purpose: To evaluate the incidence and risk factors of post-intravitreal injection (IVI) endophthalmitis in a single center modified operating room (OR) setting. Methods: In a retrospective chart review study, patients who underwent IVI in a modified OR between September 2014 and November 2016 were included. Cases of post-IVI endophthalmitis were identified from the Hospital Infection Control Committee records, which tracks all post-procedure infections. Results: 51 472 IVIs (37 814 patients) including 13 658 bilateral simultaneous injections were performed during the study period. There were 17 cases of endophthalmitis (0.033%, 95% CI 0.019%-0.052%). There were no cases of bilateral endophthalmitis. Age, sex, indication for IVI, simultaneous bilateral injections, number of previous injections, and type of injected drug were not significantly associated with incidence of endophthalmitis. Conclusion: Post-IVI endophthalmitis is rare in this modified OR setting. Simultaneous bilateral IVIs and on-site preparation of injections are safe under these conditions. © 2019, © 2019 Taylor & Francis Group, LLC.