Alopecic and Aseptic Nodule of the Scalp & Cutis Verticis Gyrata: When Rarities Meet Publisher



Zartab H^{1, 2} ; Iranmanesh B¹ ; Amiri R¹ ; Shamsimeymansi S¹
Source: Iranian Journal of Dermatology Published:2021

Abstract

Background: Alopecic and aseptic nodule of the scalp (AANS) is a rare entity characterized by the presence of sterile, culture-negative nodules/cysts and areas of non-scarring alopecia. Methods: We describe a case on the vertex of a 26-year-old man with a two-week history of a nodular, moderately-fluctuant, alopecic lesion. The patient also had cutis verticis gyrata (CVG). Results: The aspirate culture was negative and histopathologic findings were nonspecific. We also performed a trichoscopy of the lesion. After eight weeks, the patient showed dramatic clinical response to doxycycline and a dose of intralesional corticosteroid. Conclusion: This is the first report of the simultaneous occurrence of AANS and primary essential CVG. AANS is a probably under-reported cause of non-scarring alopecia with a rapid and dramatic response to non-surgical treatment and a generally good prognosis. © 2021 Iranian Society of Dermatology.