Exploring the Relationship Among Malnutrition, Intake of Various Food Groups, and Sarcopenia in Elderly Population: A Cross-Sectional Analysis Publisher



Mm Mousavinasab Mohammad MEHDI ; A Khavandegar ARMIN ; H Fakhrzadeh HOSSEIN ; M Moodi MITRA ; K Karimi KEYVAN ; S Salehi SARMAD ; M Khorashadizadeh MASOUMEH ; H Ejtahed Haniehsadat S ; F Sharifi FARSHAD
Source: Health Science Reports Published:2025

Abstract

Background and Aims: Malnutrition and specific food groups may cause sarcopenia in elderly persons. Methods: A cross-sectional analysis of an ongoing cohort study (Birjand Longitudinal Aging Study) was performed in this study. Data from elderly people was collected from September 2018 to April 2019. Gait speed, handgrip strength, and muscle mass determined sarcopenia and likely sarcopenia. A Mini Nutritional Assessment (MNA) questionnaire was used to assess malnutrition. Regression analyses reported odds ratios (OR) with 95% confidence intervals (CI), adjusted for confounders, and determined statistical significance at a p-value of less than 0.05. Potential confounders, including marital status, education, physical activity, smoking, polypharmacy, BMI, cancer, kidney stones, liver dysfunction, and vitamin D consumption were also considered in the adjusted regression models. Results: Data from 1344 elderly participants revealed that 136 individuals (10.11%) had sarcopenia, while 417 participants (31.02%) were identified with probable sarcopenia. The mean age (± SD) of the total participants was 69.7 (7.5) years. In the crude models, consumption of animal protein sources (OR = 0.59, 95% CI = 0.37–0.96) as well as fruits and vegetables (OR = 0.52, 95% CI = 0.32–0.85) had lower odds of sarcopenia. Milk and dairy products also had lower odds of sarcopenia by 37% (OR = 0.63, 95% CI = 0.41–0.98). After correcting for confounders, most relationships disappeared and no dietary group predicted sarcopenia. Malnutrition increased the odds of sarcopenia in the crude model (OR = 2.82, 95% CI = 1.93–4.12) and after age and sex adjustment (aOR = 2.05, 95% CI = 1.33–3.15). Besides, malnutrition also increased probable sarcopenia in the fully adjusted model for all confounding factors (aOR = 1.36, 95% CI = 1.03–1.81). Conclusion: Malnutrition may increase the risk of sarcopenia in older adults. Consuming animal protein, fruits, vegetables, and dairy products decreases the odds of sarcopenia slightly. Long-term studies are needed to confirm these findings. © 2025 Elsevier B.V., All rights reserved.