Plants From Genus Dracocephalum in Iran: Pharmacology and Phyto-Chemistry Overview Publisher Pubmed



Moghaddam HH¹ ; Emadi F² ; Esmaeiljamaat E³ ; Kamalinejad M⁴ ; Alijaniha F² Show Affiliations
Source: Current Drug Discovery Technologies Published:2022

Abstract

Background: Genus Dracocephalum belongs to the Lamiaceae family, representing 11 species in Iran, containing D. ghahremanii Jamzad, D. lindbergii Rech. F, D. oligadenium Bornm. & Gauba, D. kotschyi Boiss., D.multicaule, D.Aucheri, D.Subcapitatum, D.Thymifolium, D.Moldavica, D. polychaetum Borm, and D. surmandinum Rech.f. The current study aimed to investigate the morphological and phytochemical properties of Dracocephalum species in Iran and their pharmacological effects. Methods: The search was restricted to scientific articles from PubMed, Google Scholar, Science Di-rect, SpringerLink, and Scopus. The search was limited to scientific journals, books, and book chap-ters focusing on the medicinal properties of Dracocephalum in Iran for the era from 1993 to 2020. Results: Findings show that Dracocephalum species were utilized to treat various disorders in traditional medicine. Phytochemical studies show that the main constituents isolated from the plant consist of lignans, phytosterol, flavonoids, phenols, alkaloids, Sesquiterpenes, and oxygenated and hydro car-bonated monoterpenes. These main components are responsible for antihyperlipidemic, antimicrobial, anticancer, antispasmodic, antioxidant, and cardiovascular effects of the plant. Conclusion: This plant has a good potential for drug discovery and curing different diseases. There-fore, more research will be done on the Iranian species of Dracocephalum based on clinical and ani-mal studies to develop an effective drug formulation. © 2022 Bentham Science Publishers.