Tehran University of Medical Sciences

Science Communicator Platform

Stay connected! Follow us on X network (Twitter):
Share this content! By
The Comparison of Fennel and Mefenamic Acid Effects on Postpartum After Pain



Golian Tehrani S1 ; Mirmohammadali M1 ; Soltani Moghadam A2 ; Mehran A3 ; Taghi Zadeh M4 ; Baleghi M5
Authors

Source: Journal of Babol University of Medical Sciences Published:2015

Abstract

BACKGROUND AND OBJECTIVE: Postpartum pain and painful uterine contractions normally occur after childbirth and are regarded as one of the most common problems after delivery. Postpartum pain is significantly intensified by increased parity. Therefore, mothers are forced to use chemical drugs to inhibit this pain. Considering the side-effects of chemical drugs and the growing tendency towards herbal medicines, we aimed to compare the effects of fennel extracts and mefenamic acid on postpartum pain. METHODS: This single-blind, clinical trial was conducted on 86 mothers with postpartum pain after vaginal delivery at Baharloo Hospital in Tehran, Iran in 2014- 2015. Subjects were randomly divided into two groups (43 cases per group), receiving fennelin (fennel extracts) and mefenamic acid capsules. Postpartum pain was measured two hours after childbirth, using Visual Analogue Scale (VAS). Volunteers with scores higher than four were included in the study. Pain intensity was measured by VAS before and one hour after each round of intervention. Subjects used the medicines four times a day (with 4-6 hour intervals). The collected data were statistically analyzed (IRCT: 2014020515338N2) FINDINGS: The mean score of pain before the intervention was 6.47±0.797 in the mefenamic acid group and 6.35±0.752 in the fennel group. In both groups, pain score significantly reduced one hour after using medicines in comparison with the pre-treatment period (1.90±0.56 and 1.70±0.74 in the mefenamic acid and fennel groups, respectively) (p<0.05). During the study, fennel was more effective than mefenamic acid in pain reduction. The same finding was reported after the study during the fourth round of intervention (88±0.70 and 1.19±0.76 in the fennel and mefenamic acid groups, respectively). CONCLUSION: According to the results of this study, fennel, similar to mefenamic acid, could be suggested as an effective herbal medicine for pain reduction in mothers with complaints of postpartum pain. © 2015, Babol University of Medical Sciences. All rights reserved.
Other Related Docs
5. The Effect of Valerian and Ginger on Dysmenorrhea: A Randomized Clinical Trial, International Journal of Women's Health and Reproduction Sciences (2020)
6. Comparison of the Effect of Citrus Arantium and Salvia Officinalis Aroma on Post-Cesarean Section Pain, Iranian Journal of Obstetrics# Gynecology and Infertility (2017)
9. A Systematic Review of the Uterine Relaxant Effect of Herbal Sources, Current Pharmaceutical Biotechnology (2016)
10. The Effect of Fennel Oral Capsules on Physical Symptoms Caused by Menopause in Women, Iranian Journal of Obstetrics# Gynecology and Infertility (2017)
15. Mumijo Attenuates Chemically Induced Inflammatory Pain in Mice, Alternative Therapies in Health and Medicine (2015)
19. Piroxicam Reduces Acute and Chronic Pain Response in Type 1 Diabetic Rats, Journal of Basic and Clinical Physiology and Pharmacology (2021)