Effect of Alhagi Maurorum Distillate on Ureteral Stone Expulsion: A Single-Blind Randomized Trial Publisher



Aryaeefar MR¹ ; Khakbaz A² ; Akbari S² ; Movahedi A³ ; Gazerani A¹ ; Bidkhori M⁴ ; Moeini V¹
Source: Journal of Herbal Medicine Published:2022

Abstract

Introduction: The aim of this trial was to examine the effect of Alhagi maurorum distillate on ureteral stone expulsion. Methods: A randomized, single-blind, clinical trial was conducted on patients suffering from renal colic. The patients were assigned to control and intervention groups. The patients in the control group received routine treatment while the patients in the intervention group received 150 cc Alhagi maurorum distillate in three doses every day in addition to routine treatment. The duration of treatment was four weeks in both groups. Cox regression was used to assess the effect of the intervention on time of stone excretion. Results: One hundred and ten patients (75 men and 35 women) were included according to the inclusion and exclusion criteria. No significant difference was found in demographic characteristics and stone size and location between intervention and control groups. Time of removal was significantly shorter in the intervention group (HR = 5.12, P < 0.001) based on an adjusted model. Conclusion: The results suggest that depending on the size and location of the stone, Alhagi maurorum distillate may have a positive effect on the rate of stone removal from the ureter. © 2022 Elsevier GmbH