Production of Sars-Cov-2 Antibodies and Emergence of the Clinical Symptoms of Covid-19 Publisher Pubmed



Hormati A^{1, 2} ; Poustchi H³ ; Ghadir MR² ; Jafari S⁴ ; Jafari N⁵ ; Ashtari A⁶ ; Ahmadpour S² Show Affiliations
Source: Iranian Journal of Allergy# Asthma and Immunology Published:2021

Abstract

Coronavirus disease 2019 (COVID-19) is a worldwide public health problem that has attracted much attention due to its clinical findings. Measurement of IgG and IgM antibodies is of great importance for researchers and it will help to develop a new diagnostic and therapeutic method in clinical care. In this cross-sectional study, we aim to measure the IgG and IgM antibody levels in 401 suspected COVID-19 volunteers. We also measure the time duration for the appearance of IgG and IgM antibodies from the onset of symptoms to sampling time. Of 401 participants enrolled in the study, 255 (63.59%) were healthy, 79 (19.70%) were a carrier, 59 (14.71%) were cured and 8 (1.99%) were borderline. Of 142 subjects diagnosed with COVID-19, 41 (28.87%) presented with gastrointestinal (GI) symptoms, 83 (58.45%) had no GI symptoms, and 18 (12.68%) were asymptomatic. According to our findings, the measurement of IgG and IgM antibodies will provide the tool for the diagnosis of COVID-19 and significantly boost research into novel diagnostic and therapeutic approaches. Copyright © 2021 Hormati et al.