A Case Report of Primary Intra-Abdominal Synovial Sarcoma and Review of the Literature; [Reporte De Un Caso De Sarcoma Sinovial Intraabdominal Primario Y Revision De La Literatura] Publisher



Arab M¹ ; Talayeh M² ; Teymoordash SN² ; Afsharmoghadam N³ ; Nouri B⁴ ; Ghavami B⁵
Source: Clinica e Investigacion en Ginecologia y Obstetricia Published:2022

Abstract

Synovial sarcoma is a well-recognized soft tissue malignancy in adult population. Primary intraabdominal synovial sarcoma is a rare occurrence, of which 1% has retroperitoneal location. These are firm, rounded, slowly growing, well-circumscribed tumors which can sometimes be of multinodular texture. Histopathology and Immunohistochemistry (IHC) aid in confirming the diagnosis. Nearly 90% of the cases have an associated chromosomal translocation (X; 18), (p11; q11). Given its rare occurrence, management of this malignancy is challenging, though radical surgery combined with chemotherapy and radiotherapy have been described. A 54-year-old, grand multiparous lady was referred to gynecologic oncology clinic due to a large pelvic mass and abnormal uterine bleeding. Pelvic MRI showed solid cystic pelvic mass in the left adnexa. She underwent laparotomy and bilateral salpingo-oophorectomy, hysterectomy, omentectomy and pelvic lymphadenectomy. Final pathology report revealed synovial sarcoma. Synovial sarcoma should be considered in the differential diagnosis of abdomino-pelvic masses in young and middle-aged patients. © 2021