Isolation of Phenolic Derivatives and Essential Oil Analysis of Prangos Ferulacea (L.) Lindl. Aerial Parts



Delnavazi MR¹ ; Soleimani M¹ ; Hadjiakhoondi A¹ ; Yassa N¹ Show Affiliations
Source: Iranian Journal of Pharmaceutical Research Published:2017

Abstract

Prangos ferulacea (L.) Lindl. (Apiaceae) is a medicinal plant distributed in Mediterranean regions, Caucasia and southwest of Asia. In the present study phytochemical constituents of the extract obtained from the aerial parts of P. ferulacea were investigated using various chromatographic and spectroscopic methods. Essential oil of the plant aerial parts was also analyzed using GC-MS. Five phenolic derivatives, isoimperatorin (1), ferudenol (2), caffeic acid glucosyl ester (3), isorhamnetin-3-O-β-D-glucopyranoside (4) and quercetin-3-O-β-D-glucopyranoside (5) were isolated from the aerial parts of P. ferulacea and their structures were elucidated using1H-NMR,13C-NMR, EI-MS and UV spectral analyses. Twenty-seven compounds were also identified in the essential oil of plant aerial parts, of which β-pinene (43.1%), α-pinene (22.1%) and δ-3-carene (16.9%) were characterized as main compounds. The results of this study introduce P. ferulacea as a source of potentially bioactive phenolic compounds and suggest it as an appropriate candidate for further studies. © 2017 by School of Pharmacy.