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Prevalence of Hsv, Varicella-Zoster, Cmv, Ebv and Hpv in the Oral Cavity and the Larynx Carcinoma in Iran Publisher



Dayyani F1 ; Tavakolian S2 ; Goudarzi H2 ; Biucki FY3 ; Faghihloo E2
Authors
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Authors Affiliations
  1. 1. Human Viral Vaccine Department, Razi Vaccine and Serum Research Institute, Agricultural Research, Education and Extension Organization (AREEO), Karaj, Iran
  2. 2. Department of Microbiology, School of Medicine, Shahid Beheshti University of Medical Sciences, Tehran, Iran
  3. 3. Pathology Department, Amiralam Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Future Virology Published:2021


Abstract

Introduction: Viral diseases can have roles in oral cavity and larynx carcinoma. However, the relationship between HPV, herpetic infection and these cancers is not clear. Materials & methods: DNA of tissues from oral and larynx carcinoma was extracted and the presence of HPV, HSV-1, HSV-2, EBV, CMV and Varicella Zoster virus was detected. Results: We detected five HSV-1 in oral cavity cancer and two HSV-1 in larynx carcinoma. Also, four and two HPV-positive in oral cavity and larynx carcinoma were found, respectively. There were five HPV type 18 and one HPV type 31. None of our samples were infected with EBV, CMV, HSV-2 and Varicella Zoster virus. Conclusion: A higher prevalence of HPV and HSV-1 in cancerous tissues in comparison with normal ones was detected. © 2021 Future Medicine Ltd.