Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score

Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score Publisher Pubmed

Naddei R^{1, 2} ; Ridella F³ ; Bovis F⁴ ; Trincianti C³ ; Avrusin I⁵ ; Januskeviciute G⁶ ; Burrone M³ ; Rebollogimenez A¹ ; Minden K^{7, 8} ; Ekelund M^{9, 10} ; Barone P¹¹ ; Rumbarozenfelde I¹² ; Shafaie N¹³ ; Swart JF¹⁴ Show All Authors

Naddei R^{1, 2}
Ridella F³
Bovis F⁴
Trincianti C³
Avrusin I⁵
Januskeviciute G⁶
Burrone M³
Rebollogimenez A¹
Minden K^{7, 8}
Ekelund M^{9, 10}
Barone P¹¹
Rumbarozenfelde I¹²
Shafaie N¹³
Swart JF¹⁴
Ruperto N¹⁵
Ravelli A¹⁶
Consolaro A^{1, 3}

Show Affiliations

1. U.O.C. Reumatologia e Malattie Autoinfiammatorie, IRCCS Istituto Giannina Gaslini, Genova, Italy
2. Dipartimento di Scienze Mediche Traslazionali, Universita degli Studi di Napoli Federico II, Naples, Italy
3. Dipartimento di Neuroscienze, Riabilitazione, Oftalmologia, Genetica e Scienze Materno Infantili (DINOGMI), Universita degli Studi di Genova, Genoa, Italy
4. Dipartimento di Scienze della Salute (DISSAL), Universita degli Studi di Genova, Genoa, Italy
5. Department of Hospital Pediatrics, Saint-Petersburg State Pediatric Medical University, Saint Petersburg, Russian Federation
6. Centre Medical Pluridisciplinaire Argenteuil, Argenteuil, France
7. Department of Pediatric Respiratory Medicine, Immunology and Critical Care Medicine, Charite - Universitatsmedizin Berlin, Freie Universitat Berlin, Humboldt- Universitat zu Berlin, Berlin, Germany
8. Deutsches Rheuma-Forschungszentrum, Berlin, Germany
9. Department of Pediatrics, Ryhov County Hospital, Jonkoping, Sweden
10. Department of Women's and Children's Health, Uppsala University, Uppsala, Sweden
11. Pediatric Rheumatology Unit, Department of integrated Maternal-Child and Reproduction Activity, AOU 'Policlinico-San Marco', Catania, Italy
12. Faculty of Medicine and Life Sciences, University of Latvia, Riga, Latvia
13. Department of Pediatrics and Rheumatology, Rheumatology Research Centre, Shariati Hospital, Teheran, Iran
14. Department of Pediatric Immunology and Rheumatology, Wilhelmina Children's Hospital, Utrecht, Netherlands
15. UOC Gaslini Trial Centre, Servizio di Sperimentazioni Cliniche Pediatriche, IRCCS Istituto Giannina Gaslini, Genova, Italy
16. IRCCS Istituto Giannina Gaslini, Genoa, Italy

Source: Rheumatology Published:2025

Abstract

Objective: To develop parent- and child-centred versions of the Juvenile Arthritis Disease Activity Score (JADAS) and to provide preliminary evidence of their validity. Methods: Validation analyses were conducted on two large multinational datasets of patients with juvenile idiopathic arthritis (JIA) and included assessment of construct validity, internal consistency and structure, discriminative validity, responsiveness to change, and predictive validity. Results: The parJADAS and patJADAS include four parent/patient-reported outcomes, each measured on a 0-10 scale: assessment of overall disease activity; rating of pain intensity; assessment of activity of joint disease; and duration of morning stiffness. Both scores are calculated as the simple linear sum of the scores of their four components, which yield for both of them a global score of 0-40. The parJADAS and patJADAS demonstrated good construct validity, yielding high correlations with other JIA composite disease activity measures and moderate correlations with physician global rating and joint counts. Internal consistency was satisfactory, with Cronbach's α > 0.80, and exploratory factor analysis showed that both indices are monodimensional. Both instruments discriminated well between different disease states, with discriminative ability being unaffected by the presence of damage; proved able to predict important disease outcomes; and showed fair responsiveness to clinically important change, with standardized response mean of 0.71. Conclusion: Both parJADAS and patJADAS were found to possess good measurement properties and to serve as a surrogate of physicians' evaluations. Regular home completion of the two instruments through digital technologies offers a suitable and pragmatic approach to deliver remote symptom monitoring and telehealth. © 2024 The Author(s). Published by Oxford University Press on behalf of the British Society for Rheumatology. All rights reserved.

2. The Farsi Version of the Juvenile Arthritis Multidimensional Assessment Report (Jamar), Rheumatology International (2018)

Experts (# of related papers)

Seyed Reza Raeeskarami (1)

Vahid Ziaee (1)

Style	Citing Format
MLA	Naddei R, et al.. "Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score." Rheumatology, vol. 64, no. 4, 2025, pp. 2143-2152.
APA	Naddei R, Ridella F, Bovis F, Trincianti C, Avrusin I, Januskeviciute G, Burrone M, Rebollogimenez A, Minden K, Ekelund M, Barone P, Rumbarozenfelde I, Shafaie N, Swart JF, Ruperto N, Ravelli A, Consolaro A (2025). Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score. Rheumatology, 64(4), 2143-2152.
Chicago	Naddei R, Ridella F, Bovis F, Trincianti C, Avrusin I, Januskeviciute G, Burrone M, et al.. "Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score." Rheumatology 64, no. 4 (2025): 2143-2152.
Harvard	Naddei R et al. (2025) 'Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score', Rheumatology, 64(4), pp. 2143-2152.
Vancouver	Naddei R, Ridella F, Bovis F, Trincianti C, Avrusin I, Januskeviciute G, et al.. Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score. Rheumatology. 2025;64(4):2143-2152.
BibTex	@article{ author = {Naddei R and Ridella F and Bovis F and Trincianti C and Avrusin I and Januskeviciute G and Burrone M and Rebollogimenez A and Minden K and Ekelund M and Barone P and Rumbarozenfelde I and Shafaie N and Swart JF and Ruperto N and Ravelli A and Consolaro A}, title = {Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score}, journal = {Rheumatology}, volume = {64}, number = {4}, pages = {2143-2152}, year = {2025} }
RIS	TY - JOUR AU - Naddei R AU - Ridella F AU - Bovis F AU - Trincianti C AU - Avrusin I AU - Januskeviciute G AU - Burrone M AU - Rebollogimenez A AU - Minden K AU - Ekelund M AU - Barone P AU - Rumbarozenfelde I AU - Shafaie N AU - Swart JF AU - Ruperto N AU - Ravelli A AU - Consolaro A TI - Development and Initial Validation of Parent and Child Versions of the Juvenile Arthritis Disease Activity Score JO - Rheumatology VL - 64 IS - 4 SP - 2143 EP - 2152 PY - 2025 ER -

Science Communicator Platform

Authors

Authors Affiliations

Abstract