Tehran University of Medical Sciences

Science Communicator Platform

Share By
Emerging Role of Lncrnas in the Etiology of Recurrent Implantation Failure Publisher Pubmed



Fathi M1 ; Ghahghaeinezamabadi A2 ; Ghafourifard S1
Authors

Source: Pathology Research and Practice Published:2024


Abstract

Recurrent implantation failure (RIF) is a complex clinical entity with several molecular pathways contributing to its pathogenesis. Long non-coding RNAs (lncRNAs) have recently been found to affect the normal implantation, thus aberrant expression of these transcripts is involved in RIF. Altered expression of HOXA11-AS, NONHSAT193031.1, NONHSAT053761.2, NONHSAT083203.2, LUCAT1, PART1, TUNAR, LINC02190, lncSAMD11–1:1 and H19 has been reported in this condition. Moreover, polymorphisms within some lncRNAs have been shown to be associated with miscarriage/RIF. The current review article summarizes the recent data about the role of lncRNAs in RIF. This information would pave the way for identification of the molecular events in this context. © 2023
Related Docs
View other Related Docs
1. Construction of Circrna-Mirna-Mrna Network in the Pathogenesis of Recurrent Implantation Failure Using Integrated Bioinformatics Study, Journal of Cellular and Molecular Medicine (2022)
2. Non-Coding Rnas in Recurrent Implantation Failure, Clinica Chimica Acta (2024)
3. Hsa_Circ_0004121 and Hsa_Circ_0030162 Differentially Expressed in Plasma of Patients With Recurrent Implantation Failure, Reports of Biochemistry and Molecular Biology (2024)
Experts (# of related papers)
View all Related Experts
Mohammad Hossein Modarressi (1)
Zahra Azizi Varzaneh (1)
Other Related Docs
4. Impact of Mirnas in the Pathoetiology of Recurrent Implantation Failure, Molecular and Cellular Probes (2024)
5. Identification of Lncrnas Associated With the Progression of Acute Lymphoblastic Leukemia Using a Competing Endogenous Rnas Network, Oncology Research (2022)
6. Identifying Shared Molecular Landscape Between Uterine Fibroids and Recurrent Implantation Failure: An Integrated Bioinformatics Study, Heliyon (2025)
7. A Computational Framework to Infer Prostate Cancer-Associated Long Noncoding Rnas and Analyses for Identifying a Competing Endogenous Rna Network, Genetic Testing and Molecular Biomarkers (2021)
8. An Overview of Long Noncoding Rnas: Biology, Functions, Therapeutics, Analysis Methods, and Bioinformatics Tools, Cell Biochemistry and Function (2022)
9. Micrornas and Long Non-Coding Rnas As Biomarkers for Polycystic Ovary Syndrome, Journal of Cellular and Molecular Medicine (2022)
10. Candidate Prognostic Lncrnas Including C2orf49-Dt, Capn10-Dt, Loc105371795 As Potential Biomarkers for Colorectal Cancer, Biochemical Genetics (2025)