Dna Phosphoramidites

Dna Phosphoramidites Publisher

Foroumadi R¹ ; Baeeri M² ; Asgarian S¹

Show Affiliations

1. Department of Pharmacology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran
2. Toxicology and Diseases Group, Pharmaceutical Sciences Research Center (PSRC), The Institute of Pharmaceutical Sciences (TIPS), Tehran University of Medical Sciences, Tehran, Iran

Source: Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 Published:2023

Abstract

DNA Phosphoramidites are utilized in the preferred approach for industrial DNA synthesis. It is currently the exclusive economically feasible chemistry method capable of producing the high quantity of DNA. A phosphoramidite molecule has a phosphite group rather than the usual phosphate in nucleotides, as well as four distinct protecting groups. These protecting groups provide a stable protection but can be readily eliminated when needed. This enables DNA scientists to expose only the reactive centers required to generate a DNA-like molecule, allowing for precise control over synthesis chemistry. According to experimental studies, these structures were not toxic in short- or long-term. However, there is inadequate evidence on human toxic effects. © 2024 Elsevier Inc. All rights reserved.

Style	Citing Format
MLA	Foroumadi R, Baeeri M, Asgarian S. "Dna Phosphoramidites." Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, vol. 3, no. , 2023, pp. V3-913.
APA	Foroumadi R, Baeeri M, Asgarian S (2023). Dna Phosphoramidites. Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, 3(), V3-913.
Chicago	Foroumadi R, Baeeri M, Asgarian S. "Dna Phosphoramidites." Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 3, no. (2023): V3-913.
Harvard	Foroumadi R, Baeeri M, Asgarian S (2023) 'Dna Phosphoramidites', Encyclopedia of Toxicology# Fourth Edition: Volume 1-9, 3(), pp. V3-913.
Vancouver	Foroumadi R, Baeeri M, Asgarian S. Dna Phosphoramidites. Encyclopedia of Toxicology# Fourth Edition: Volume 1-9. 2023;3():V3-913.
BibTex	@article{ author = {Foroumadi R and Baeeri M and Asgarian S}, title = {Dna Phosphoramidites}, journal = {Encyclopedia of Toxicology# Fourth Edition: Volume 1-9}, volume = {3}, number = {}, pages = {V3-913}, year = {2023} }
RIS	TY - JOUR AU - Foroumadi R AU - Baeeri M AU - Asgarian S TI - Dna Phosphoramidites JO - Encyclopedia of Toxicology# Fourth Edition: Volume 1-9 VL - 3 IS - SP - V3 EP - 913 PY - 2023 ER -

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