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Simultaneous Bilateral Total Knee Arthroplasty in Patients With Haemophilia: A Safe and Cost-Effective Procedure? Publisher



Mortazavi SMJ1 ; Haghpanah B1 ; Ebrahiminasab MM1 ; Baghdadi T1 ; Hantooshzadeh R2 ; Toogeh G3
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Authors Affiliations
  1. 1. Investigation was performed in Joint Reconstruction Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Ministry of Health and Medical Education, Office of Organ Transplantation and Special Diseases, Tehran, Iran
  3. 3. Tehran University of Medical Sciences, Thrombosis Hemostasis Research Center, Tehran, Iran

Source: Haemophilia Published:2016


Abstract

Introduction: Haemophilic arthropathy of the knee is usually a bilateral affliction. The patients usually refer for treatment in young ages and do not have major comorbidities, being fit for bilateral simultaneous total knee arthroplasty. Aim: In this study, we assessed the safety and cost-effectiveness of simultaneous bilateral surgery in patients with haemophilia. Methods: Between April 2010 and April 2012, eight patients (16 knees) underwent bilateral simultaneous and 19 patients (19 knees) underwent unilateral total knee arthroplasty (TKA) at our institution. We compared the range of motion and flexion contracture, KSS, WOMAC knee score and SF36 quality of life score between two groups. The duration of hospital stay, coagulation factor consumption and all inpatient costs were recorded. The average follow-up was 26 and 29 months in unilateral and bilateral groups respectively. Results: At the conclusion of the study, the KSS and WOMAC and SF36 scores were not significantly different between the two groups. Mean ROM and flexion contracture did not differ significantly. The mean length of hospital stay was 15 days for bilateral patients and 12 days for unilateral patients, the difference being non-significant. None of our patients needed transfusion in any group. The cost of simultaneous bilateral TKA was about half of the expenses of staged bilateral TKA. Conclusion: Simultaneous bilateral TKA seems to be a safe and cost-effective approach without increasing the rate of complications in patients' bilateral haemophilic knee arthropathy. The procedure is, at least, as effective as staged unilateral knee arthroplasty in improving the patients' quality of life. © 2016 John Wiley & Sons Ltd.
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1. Total Knee Arthroplasty in Patients With Hemophilia: What Do We Know?, Archives of Bone and Joint Surgery (2020)
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