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Adopting Clinical Practice Guidelines for Pharmacologic Managementofacutespinalcordinjuryfromadeveloped World Context to a Developing Global Region Publisher Pubmed



Jazayeri SB1 ; Maroufi SF1, 2 ; Ghodsi Z1, 3 ; Ghawami H4 ; Pourrashidi A5 ; Amirjamshidi A5 ; Mojtahedzadeh M5, 6 ; Arabkheradmand J7 ; Farahbakhsh F1, 8 ; Shabany M1, 2 ; Faghihjouibari M9 ; Fehlings MG10 ; Kwon BK11, 12 ; Harrop JS13 Show All Authors
Authors
  1. Jazayeri SB1
  2. Maroufi SF1, 2
  3. Ghodsi Z1, 3
  4. Ghawami H4
  5. Pourrashidi A5
  6. Amirjamshidi A5
  7. Mojtahedzadeh M5, 6
  8. Arabkheradmand J7
  9. Farahbakhsh F1, 8
  10. Shabany M1, 2
  11. Faghihjouibari M9
  12. Fehlings MG10
  13. Kwon BK11, 12
  14. Harrop JS13
  15. Rahimimovaghar V1, 3, 9, 14, 15, 16
Show Affiliations
Authors Affiliations
  1. 1. Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Faculty of Medicine, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Brain and Spinal Cord Injury Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Neuropsychology Division, Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Program in Clinical Pharmacy and Critical Care, Faculty of Pharmacy, Tehran, Iran
  7. 7. Defence Health Research C, Tehran, Iran
  8. 8. Sports Medicine Research Center, Neuroscience Institute, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Department of Neurosurgery, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran
  10. 10. University of Toronto Spine Program, Toronto Western Hospital, Toronto, ON, Canada
  11. 11. International Collaboration on Repair Discoveries (ICORD), University of British Columbia, Vancouver, BC, Canada
  12. 12. Department of Orthopaedics, Division of Spine, University of British Columbia, Vancouver, BC, Canada
  13. 13. Department of Neurological and Orthopedic Surgery, Thomas Jefferson University, Philadelphia, PA, United States
  14. 14. Universal Scientific Education and Research Network (USERN), Tehran, Iran
  15. 15. Institute of Biochemistry and Biophysics, University of Tehran, Tehran, Iran
  16. 16. Spine Program, University of Toronto, Toronto, Canada

Source: Archives of Iranian Medicine Published:2022


Abstract

Background: Proper utilization of high-quality clinical practice guidelines (CPGs) eliminates the dependence of patients’ outcomes on the ability and knowledge of “individual” health care providers and reduces unwarranted variation in care. The aim of this study was to adapt/adopt two CPGs for pharmacologic management of acute spinal cord injury (SCI) using guideline adaptation methods. Methods: This study was conducted based on the ADAPTE process. Following establishment of an organizing committee and choosing the health topics, we appraised the quality of the CPGs using the Appraisal of Clinical Guidelines for Research & Evaluation II (AGREE II). Then, the authors extracted and categorized suggestions according to Population, Intervention, Professions, Outcomes and Health care setting (PIPOH). The decision-making process was based on systemic evaluation of each suggestion, utilizing a combination of AGREE II scores, the quality of supporting evidence for or against each suggestion and the triad of feasibility, acceptance and adoptability for the Iranian health-care context. Results: Two guidelines were included in the adaptation process. Based on high-quality of these guidelines and the feasibility and adoptability evaluation of the organizing committee, we decided to adopt the suggestion of both guidelines. Overall, seven suggestions were extracted from the source guidelines. Conclusion: This work provides a framework to apply guidelines for acute SCI to the developing regions of the world. Attempts should be made to implement these suggestions in order to improve the health outcomes of Iranian SCI patients. © 2022 Academy of Medical Sciences of I.R. Iran. All rights reserved.