Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease?

Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease? Publisher Pubmed

Talebi A¹ ; Kahdouei MT² ; Memar EH³ ; Ashjaei B⁴ ; Raji H⁴ ; Adel MG⁴

Show Affiliations

1. Pediatric Disease Research Center, Guilan University of Medical Science, Rasht, Iran
2. Medical school, Tehran University of Medical Science, Tehran, Iran
3. Children’s Medical Center, Tehran University of Medical Science, Tehran, Iran
4. Department of Pediatric Surgery, Children’s Medical Center, Tehran University of Medical Science, Tehran, Iran

Source: BMC Research Notes Published:2024

Abstract

Objective: The aim of this study is to investigate the accuracy of utilizing neural fiber trunk diameter in accurately diagnosing the length of the aganglionic segment in patients definitively diagnosed with Hirschsprung’s disease. Results: In this study, 40 patients (19 males, 21 females; mean age 2.5 ± 2.2646 years) were assessed for Hirschsprung’s disease. Constipation was the main symptom (75%), followed by abdominal issues. All underwent contrast enema and rectal suction biopsy for diagnosis, followed by surgery (predominantly Soave and Swensen techniques). Majority (85%) had rectosigmoid involvement. Neural fiber diameter was measured, with 52.5% ≤40 μm and 47.5% >40 μm. Statistical analysis showed 40% sensitivity(CI:95%) and 47% specificity(CI:95%) with a cutoff of 40.5 μm. Cohen’s kappa index for aganglionic segment size was 0.7. © The Author(s) 2024.

Style	Citing Format
MLA	Talebi A, et al.. "Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease?." BMC Research Notes, vol. 17, no. 1, 2024, pp. -.
APA	Talebi A, Kahdouei MT, Memar EH, Ashjaei B, Raji H, Adel MG (2024). Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease?. BMC Research Notes, 17(1), -.
Chicago	Talebi A, Kahdouei MT, Memar EH, Ashjaei B, Raji H, Adel MG. "Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease?." BMC Research Notes 17, no. 1 (2024): -.
Harvard	Talebi A et al. (2024) 'Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease?', BMC Research Notes, 17(1), pp. -.
Vancouver	Talebi A, Kahdouei MT, Memar EH, Ashjaei B, Raji H, Adel MG. Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease?. BMC Research Notes. 2024;17(1):-.
BibTex	@article{ author = {Talebi A and Kahdouei MT and Memar EH and Ashjaei B and Raji H and Adel MG}, title = {Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease?}, journal = {BMC Research Notes}, volume = {17}, number = {1}, pages = {-}, year = {2024} }
RIS	TY - JOUR AU - Talebi A AU - Kahdouei MT AU - Memar EH AU - Ashjaei B AU - Raji H AU - Adel MG TI - Can the Diameter of Nerve Fibers Be Effectively Utilized to Enhance the Accuracy of Determining the Length of the Aganglionic Segment Compared to Intraoperative Biopsy in Patients With Hirschsprung’S Disease? JO - BMC Research Notes VL - 17 IS - 1 SP - EP - PY - 2024 ER -

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