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Ramsay-Hunt-Syndrome Associated With Unilateral Parotitis Following Covid-19 Vaccine: A Case Report Publisher



Soltanipur M1, 2 ; Yarmohammadi H2 ; Mahdavi Anari SF3 ; Karimi Nemch M4, 5 ; Taromiha A6 ; Siadat SD2, 7
Authors
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Authors Affiliations
  1. 1. General Practitioner (GP), Ebne-sina Medical Center (EMC), Tehran, Iran
  2. 2. Department of Mycobacteriology and Pulmonary Research, Pasteur Institute of Iran, Tehran, Iran
  3. 3. Department of Dermatology, Shiraz University of Medical Sciences, Shiraz, Iran
  4. 4. Student Research Committee, School of Dentistry, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Oral and Dental Diseases Research Center, Kerman University of Medical Sciences, Kerman, Iran
  6. 6. Student Research Committee, School of Medicine, Iran University of Medical Sciences, Tehran, Iran
  7. 7. Microbiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran

Source: European Archives of Oto-Rhino-Laryngology Published:2025


Abstract

Background: Varicella-zoster-virus (VZV) reactivation is a recognized complication following COVID-19 vaccination; however, Ramsay-hunt-syndrome (RHS) rarely has been reported. Case presentation: This case presents a 36-year-old immunocompetent man with features of RHS three weeks following the second dose of the BBIBP-CorV (Sinopharm) vaccine. Interestingly, he developed acute unilateral parotitis on his left side and the ultrasonography showed a 55*44*18 mm parotid gland with decreased parenchymal echogenicity. He was treated with valacyclovir, and after seven days he was discharged. Also, his parotitis was resolved by day 29 following the presentation of the first symptoms with no further complications. Conclusion: The possibility of VZV reactivation after COVID-19 vaccination is an important point and it should be noted that this reactivation might present in unusual clinical scenarios. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2025.
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