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The Effect of Date Palm (Phoenix Dactylifera L.) Pollen on the Serum Levels of Testosterone, Luteinizing, and Follicle Stimulating Hormones in Men Publisher



Karimi M1 ; Asbagh FA2 ; Safavi M3 ; Yekaninejad MS4 ; Rahimi R5 ; Pourmand G3 ; Mirzaei M6 ; Farshbafkhalili A7
Authors
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Authors Affiliations
  1. 1. Department of Iranian Traditional Medicine, School of Traditional Medicine, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Department of Obstetrics and Gynecology, IVF Unit, Yas Hospital, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Urology Research Center, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Epidemiology and Biostatistics, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran
  5. 5. Department of Traditional Pharmacy, School of Traditional Pharmacy, Tehran University of Medical Sciences, Tehran, Iran
  6. 6. Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran
  7. 7. Physical Medicine and Rehabilitation Research Center, Aging Research Institute, Tabriz University of Medical Sciences, Tabriz, Iran

Source: Current Traditional Medicine Published:2024


Abstract

Background: Date Palm Pollen (DPP) has traditionally been used to increase sexual ability and fertility. In several animal studies, the effects of this herbal medicine on testosterone, luteinizing hormone (LH), and follicle-stimulating hormone (FSH) have been shown. Objectives: This study was conducted to evaluate the effects of this drug on the serum levels of testosterone, LH, and FSH in men. Methods: In this semi-experimental study, a daily dose of 6 g dry powder of DPP in two separate doses (3 g every 12 hours) was administered orally to 30 eligible men for three months. The changes in mean serum levels of hormones were statistically evaluated after the intervention compared to the baseline. The serum concentration of the hormones was assayed through the enzyme-linked immunosorbent assay method. Data were analyzed using paired t-tests. Results: After recruitment, among 30 participants, 24 men received the intervention and finally were analyzed. The mean (SD) age and body mass index of participants were 32.85 (0.43) years and 26.5 (0.5) kg/m2. DPP significantly increased the serum levels of testosterone (from 5.31 ± 0.40 ng/mlto 6.88 ± 0.71 ng/ml; p=0.019) but did not affect the serum levels of FSH (from 4.31 ± 0.50 IU/L to 4.70 ± 0.61 IU/L; p=0.511). It also significantly decreased the serum levels of LH (from 5.65 ± 0.81 IU/L to 4.52 ± 0.90 IU/L; p= 0.033). There were no reported side effects. Conclusion: The results indicated an increasing effect of DPP on serum testosterone and decreasing effect on serum LH. However, DPP had no significant effect on FSH serum levels. © 2024 Bentham Science Publishers.