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The Mutographs Biorepository: A Unique Genomic Resource to Study Cancer Around the World Publisher



Perdomo S1 ; Abediardekani B1 ; De Carvalho AC1 ; Ferreiroiglesias A1 ; Gaborieau V1 ; Cattiaux T1 ; Renard H1 ; Chopard P1 ; Carreira C2 ; Spanu A1 ; Nikmanesh A1 ; Cardoso Penha RC1 ; Antwi SO3, 4 ; Ashtonprolla P5, 6 Show All Authors
Authors
  1. Perdomo S1
  2. Abediardekani B1
  3. De Carvalho AC1
  4. Ferreiroiglesias A1
  5. Gaborieau V1
  6. Cattiaux T1
  7. Renard H1
  8. Chopard P1
  9. Carreira C2
  10. Spanu A1
  11. Nikmanesh A1
  12. Cardoso Penha RC1
  13. Antwi SO3, 4
  14. Ashtonprolla P5, 6
  15. Canova C7
  16. Chitapanarux T8
  17. Cox R9
  18. Curado MP10
  19. De Oliveira JC11
  20. Dzamalala C12
  21. Fabianova E13
  22. Ferri L14
  23. Fitzgerald R15
  24. Foretova L16
  25. Gallinger S17
  26. Goldstein AM19
  27. Holcatova I20, 21
  28. Huertas A22
  29. Janout V23
  30. Jarmalaite S24, 25
  31. Kaneva R26
  32. Kowalski LP10, 27
  33. Kulis T28, 29
  34. Lagiou P30
  35. Lissowska J31
  36. Malekzadeh R32
  37. Mates D33
  38. Mccorrmack V34
  39. Menya D35
  40. Mhatre S36
  41. Mmbaga BT37
  42. De Moricz A38
  43. Nyirady P39
  44. Ognjanovic M40
  45. Papadopoulou K41
  46. Polesel J42
  47. Purdue MP43
  48. Rascu S44
  49. Rebolho Batista LM45
  50. Reis RM45, 46
  51. Ribeiro Pinto LF47
  52. Rodriguezurrego PA48
  53. Sangkhathat S49
  54. Sangrajrang S50
  55. Shibata T51, 52
  56. Stakhovsky E53
  57. Swiatkowska B54
  58. Vaccaro C55
  59. Vasconcelos De Podesta JR56
  60. Vasudev NS57
  61. Vilensky M58
  62. Yeung J59
  63. Zaridze D60
  64. Zendehdel K61
  65. Scelo G62
  66. Chanudet E63
  67. Wang J64
  68. Fitzgerald S64
  69. Latimer C64
  70. Moody S64
  71. Humphreys L64
  72. Alexandrov LB65, 66, 67
  73. Stratton MR64
  74. Brennan P1

Source: Cell Genomics Published:2024


Abstract

Large-scale biorepositories and databases are essential to generate equitable, effective, and sustainable advances in cancer prevention, early detection, cancer therapy, cancer care, and surveillance. The Mutographs project has created a large genomic dataset and biorepository of over 7,800 cancer cases from 30 countries across five continents with extensive demographic, lifestyle, environmental, and clinical information. Whole-genome sequencing is being finalized for over 4,000 cases, with the primary goal of understanding the causes of cancer at eight anatomic sites. Genomic, exposure, and clinical data will be publicly available through the International Cancer Genome Consortium Accelerating Research in Genomic Oncology platform. The Mutographs sample and metadata biorepository constitutes a legacy resource for new projects and collaborations aiming to increase our current research efforts in cancer genomic epidemiology globally. © 2024
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