Tehran University of Medical Sciences

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Magnetic Resonance Spectroscopy Findings of Intracranial Chondroma and Chondrosarcoma With a Non-Skull Base Origin: A Report of Two Cases Publisher



Amanpourgharaei B1 ; Bilehsavar SH2 ; Pourrashidi A3 ; Izanlou M4 ; Bastanipour Y5 ; Hashemi H6 ; Oghabian MA7 ; Nazar E8 ; Raminfard S9
Authors
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Authors Affiliations
  1. 1. Omid Institute for Advanced Biomodels, Imam-Khomeini Medical Complex, Tehran University of Medical Sciences, Tehran, Iran
  2. 2. Center of Functionally Integrative Neuroscience, Aarhus University, Aarhus, Denmark
  3. 3. Department of Neurosurgery, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  4. 4. Department of Radiology, North Khorasan University of Medical Sciences, North Khorasan, Iran
  5. 5. Department of Medical Physics and Radiology, North Khorasan University of Medical Sciences, Bojnnurd, Iran
  6. 6. Department of Radiology, School of Medicine, Advanced Diagnostic and Interventional Radiology Research Center, Imam Khomeini Hospital, Tehran University of Medical Sciences, Tehran, Iran
  7. 7. Neuroimaging and Analysis Group, Research Center for Molecular and Cellular Imaging, Advanced Medical Technologies and Equipment Institute, Tehran University of Medical Sciences, Tehran, Iran
  8. 8. Department of Pathology, Sina Hospital, Tehran University of Medical Sciences, Tehran, Iran
  9. 9. Advanced Diagnostic and Interventional Radiology Research Center, Imam Khomeini Hospital Complex, Tehran University of Medical Sciences, Tehran, Iran

Source: Iranian Journal of Radiology Published:2023


Abstract

Introduction: Intracranial chondroma and chondrosarcoma are very rare tumors that mainly originate from the base of the skull. Advanced neuroimaging studies, including magnetic resonance spectroscopy (MRS), play a pivotal role in both tumor diagnosis and presurgical planning. Case Presentation: We present two cases of intracranial cartilaginous tumors, including a chondroma and a chondrosarcoma, both of which presented with severe headaches. Due to inconclusive conventional MRI and MRS results, they were both primarily diagnosed as intra-axial brain tumors. However, pathological reports later confirmed the diagnosis of a chondroma and a chondrosarcoma. Conclusion: Based on the present findings, the use of advanced neuroimaging techniques, such as MRS, may improve diagnostic accuracy. We believe that MRS can play a significant role in the surgical planning of similar cases. Also, reporting rare cases worldwide can contribute to the improvement of radiographic diagnosis. © 2023, Author(s).