A Rare Case of Aneurysmal Bone Cyst of the Anterior Clinoid Process in an 18-Year-Old Female Mimicking Optic Neuritis Publisher



Sharifi G^{1, 2} ; Hajikarimloo B² ; Mohammadi E³ ; Paraandavaji E² ; Dilmaghani NA^{2, 4} ; Ayoobi N⁵ ; Jafari A^{1, 2} Show Affiliations
Source: Child's Nervous System Published:2024

Abstract

Background: Aneurysmal bone cyst (ABC) is an uncommon, benign, vascular multicystic bony lesion that most frequently develops in the first two decades of life. The metaphysis of long bones, pelvic, and vertebral column are the most common locations. The precise underlying pathophysiology of ABCs formation remains unclear; however, it is believed that reactive processes subsequent to trauma or vascular disturbance may play an important role. Involvement of the skull base rarely occurs with a prevalence of up to 5% of intracranial ABCs. Case presentations: An 18-year-old adolescent female with a history of progressive blurred vision since three months ago presented to our office. The brain and orbital MRI demonstrated no abnormal findings. After three months of glucocorticoid treatment with the diagnosis of multiple sclerosis, the visual impairment of the left eye deteriorated abruptly. The patient underwent an MRI and the imaging study demonstrated a well-defined 30 × 22 × 20-mm lesion at the anterior clinoid process with an extension to the optic canal and ethmoid sinus. The patient underwent pterional craniotomy, and the tumor was resected. The histopathological examination was suggestive of ABC. Conclusion: ABC and other conditions should be considered in young-age people with an early unilateral decline in vision and imaging studies should be obtained in early stages and during follow-ups. © The Author(s), under exclusive licence to Springer-Verlag GmbH Germany, part of Springer Nature 2024.