Comorbidities in Iranian Obese Psoriatic Patients Compared With Non-Obese Patients Publisher



Zargari O¹ ; Azimi SZ² ; Barat T¹ ; Lajevardi V³ ; Kazemnejad E⁴ ; Dadras MS¹ Show Affiliations
Source: Acta Medica Iranica Published:2019

Abstract

Psoriasis is a common chronic inflammatory skin disease, which is gradually being recognized as a systemic inflammatory disorder. Psoriasis and obesity are strongly linked, but there is not enough data whether obese psoriatic patients present differently from non-obese psoriatic patients. To compare the phenotype, clinical features, severity, baseline comorbidities and laboratory findings among psoriatic patients with/without obesity all the psoriatic patients, from three centers, who were receiving systemic therapy were included in the study. Patients were divided into two groups: those with obesity and those without obesity. We included 497 patients: 154 (31%) patients were obese and 343 (69%) were non-obese. Obese patients had more comorbidities, particularly hyperlipidemia, followed by hypertension and diabetes. Fasting blood sugar and serum lipids were significantly higher among obese subjects. Given the differences between obese patients and non-obese patients, the former group should be followed and managed more closely and with specific attention. © 2019 Tehran University of Medical Sciences.