In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring

In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring Publisher

Hariri Tabrizi S¹ ; Ramezani M² ; Feghhi SAH² ; Geramifar P³

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1. Department of Medical Radiation Engineering, Shahid Beheshti University, G.C., Tehran, Iran
2. Radiation Application Department, Shahid Beheshti University, G.C., Tehran, Iran
3. Research Center for Nuclear Medicine, Shariati Hospital, Tehran University of Medical Sciences, Tehran, Iran

Source: Medical and Biological Engineering and Computing Published:2020

Abstract

In vivo dosimetry of the patients treated by I-131 is important from patient dosimetry and radiation protection points of view. Knowledge of delivered dose to the target volume and adjacent normal tissues can improve the effectiveness of radioiodine treatment. Herein, design, fabrication, and assessment processes of an iodine radionuclide dosimeter (IRD) are explained. Two CsI(Tl) scintillator crystals coupled to photodiodes were used in IRD fabrication with specifications derived from Monte Carlo (MC) simulation. Linearity, sensitivity, and long-term performance of the system were tested. Delivered dose due to a known administered activity of I-131 was calculated by MC simulation which was validated based on the Medical Internal Radiation Dose (MIRD) Committee formalism, and the calibration factor was provided. Using the current mode signal acquisition method, the system showed a linear response up to 8.2 GBq radioiodine activity to prohibit the pile-up error without a need for correction factor. On the other hand, IRD was sensitive down to the rarely detectable activity of 7.4 MBq. A prototype version of the IRD system has been developed to guide the hospital staff for the safe release of iodine – administered patients and to provide an insight for physicians about the delivered dose to the thyroid and nearby organs. [Figure not available: see fulltext.]. © 2020, International Federation for Medical and Biological Engineering.

Style	Citing Format
MLA	Hariri Tabrizi S, et al.. "In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring." Medical and Biological Engineering and Computing, vol. 58, no. 4, 2020, pp. 763-769.
APA	Hariri Tabrizi S, Ramezani M, Feghhi SAH, Geramifar P (2020). In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring. Medical and Biological Engineering and Computing, 58(4), 763-769.
Chicago	Hariri Tabrizi S, Ramezani M, Feghhi SAH, Geramifar P. "In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring." Medical and Biological Engineering and Computing 58, no. 4 (2020): 763-769.
Harvard	Hariri Tabrizi S et al. (2020) 'In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring', Medical and Biological Engineering and Computing, 58(4), pp. 763-769.
Vancouver	Hariri Tabrizi S, Ramezani M, Feghhi SAH, Geramifar P. In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring. Medical and Biological Engineering and Computing. 2020;58(4):763-769.
BibTex	@article{ author = {Hariri Tabrizi S and Ramezani M and Feghhi SAH and Geramifar P}, title = {In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring}, journal = {Medical and Biological Engineering and Computing}, volume = {58}, number = {4}, pages = {763-769}, year = {2020} }
RIS	TY - JOUR AU - Hariri Tabrizi S AU - Ramezani M AU - Feghhi SAH AU - Geramifar P TI - In Vitro Evaluation of an Iodine Radionuclide Dosimeter (Ird) for Continuous Patient Monitoring JO - Medical and Biological Engineering and Computing VL - 58 IS - 4 SP - 763 EP - 769 PY - 2020 ER -

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