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Effectiveness of Massage Therapy on Fatigue and Pain in Patients With Multiple Sclerosis: A Systematic Review and Meta-Analysis Publisher



Salarvand S1 ; Heidari ME2 ; Farahi K2 ; Teymuri E2 ; Almasian M3 ; Bitaraf S4
Authors
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Authors Affiliations
  1. 1. Hepatitis Research Center, Faculty of Nursing and Midwifery, Lorestan University of Medical Sciences, Khorramabad, Iran
  2. 2. Student Scientific Research Center, School of Nursing and Midwifery, Tehran University of Medical Sciences, Tehran, Iran
  3. 3. Department of the English Language, Faculty of Medicine, Lorestan University of Medical Sciences, Khorramabad, Iran
  4. 4. Department of Epidemiology and Biostatistics, Iran University of Medical Sciences, Tehran, Iran

Source: Multiple Sclerosis Journal - Experimental# Translational and Clinical Published:2021


Abstract

Background: Fatigue and pain are prevalent symptoms of multiple sclerosis (MS) and frequent complaint in MS patients, which reduce their quality of life. This study aimed to assess the effect of massage therapy on pain and fatigue in MS Patients. Method: The original and Persian databases were searched included PubMed, web of science, embase, ovid, scopus, and the Cochrane Library, SID, and Iranedex from inception to November 2020. Studies that reported the effect of massage on fatigue and pain were included. Two investigators extracted all relevant data, independently. For deriving analysis, mean difference (MD) and standardized mean difference (SMD) were used. Result: Ten studies were eligible acoording criteria. The effect of massage on fatigue showed significant improvement (−1.62; 95% CL −2.40, −0.83; p <.00001), also results of the systematic review showed a significant reduction in pain severity. Conclusion: Massage as a complementary and non-pharmacological therapy might have been associated with alleviating fatigue and pain in M.S. patients. Based on the current study, massage intervention for MS patients could have possible clinical value for palliating pain and fatigue and improving quality of life; however, this matter needs further and more significant trial studies. © The Author(s) 2021.
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