Subacute Brucellosis-Induced Guillain-Barre Syndrome: A Case Report; [Subakut Bruselloz Ile Iliskili Guillain-Barre Sendromu: Vaka Bildirimi] Publisher



Moradipordanjani M ; Mehrighahfarrokhi A ; Moradipordanjani S ; Rahmani F
Source: Mediterranean Journal of Infection, Microbes and Antimicrobials Published:2025

Abstract

Guillain-Barre syndrome (GBS) is the most frequent cause of acute flaccid paralysis, and in two-thirds of the patients, antecedent infections have been identified. Brucellosis, a zoonotic disease, rarely leads to GBS. Herein, we present two patients with subacute brucellosis-induced GBS that were diagnosed on the basis of their clinical course and electromyography and nerve conduction velocity study results. There was a 1-month and 5-month interval between the onset of brucellosis and GBS in the two patients. The patients recovered after undergoing plasma exchange, intravenous immunoglobulin administration, and antibiotic therapy. Our findings indicate that physicians should consider brucellosis as a potential etiology of GBS and closely monitor the neurological symptoms of patients with brucellosis. © 2023 by the Infectious Diseases and Clinical Microbiology Specialty Society of Turkey Mediterranean Journal of Infection, Microbes and Antimicrobials published by Galenos Yayinevi.