Comparison of Conventional and Micro-Surgical Techniques for Gingival Augmentation by Free Gingival Grafting: A Randomized Controlled Clinical Trial Publisher Pubmed



H Aslroosta HOORI ; Gm Tehrani Ghazal MORSHEDZADEH ; S Akbari SOLMAZ ; S Yaghobee SIAMAK
Source: BMC Oral Health Published:2025

Abstract

Objectives: The objective of the present study was to compare the conventional and micro-surgical techniques to increase the keratinized gingiva width (KGW) by free gingival grafting (FGG). The primary outcome was the percentage of graft shrinkage. Clinical and esthetics results, postoperative complications, and patient-related parameters were also evaluated as secondary outcomes. Materials and methods: This randomized controlled clinical trial was conducted on 22 patients (68% females, mean age of 43.40 ± 11.21 years) who required FGG to increase their KGW. The patients were randomly assigned to two groups (n = 11) of microsurgery and conventional surgery (control). In the microsurgery group, all surgical processes (except graft harvesting) were conducted under magnification (x4- x10) using a surgical microscope. The primary outcome was graft shrinkage, measured by comparing graft dimensions over 3 months. Secondary outcomes included KGW, operative time, color match, root coverage esthetic score (RCES), healing index (HI), postoperative pain, edema, bleeding, and patient satisfaction. Data were analyzed by independent t-test, repeated measures ANOVA, Bonferroni test, and Mann-Whitney test (α = 0.05). Results: Graft shrinkage at 3 months showed no statistically significant difference between the two groups (p > 0.05). KGW increase was similar in both groups (p > 0.05). The micro-surgery group had significantly better color match (p = 0.04), faster early healing (p = 0.009), and lower pain (first week, p = 0.04) and edema (p < 0.05 on days 4–5) than the conventional group. However, the micro-surgery group required significantly more operative time (100.82 ± 19.11 min versus 78.09 ± 3.67 min; p = 0.003). Conclusion: Despite no significant difference in the primary outcome (graft shrinkage), the micro-surgical approach resulted in faster tissue healing, better color match, and reduced early postoperative pain and edema. Clinically, these advantages should be weighed against the longer operative time and equipment requirements. Trial registration: Iranian Registry of Clinical Trials IRCT20211022052841N1 registered on [05/11/2021]. © 2025 Elsevier B.V., All rights reserved.