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Leveraging Space Innovations for Cancer Breakthroughs on Earth Publisher Pubmed



Akbarialiabad H1, 2, 3 ; Jamshidi P4 ; Aminzade Z4 ; Azizi N5 ; Taha SR6 ; Sadeghian N7 ; Varghese LJK8, 9, 10 ; Kouhanjani MF12 ; Niknam N11 ; Babocs D13 ; Elassaad F14 ; Russomano T15 ; Murrell DF1, 16, 17 ; Paydar S18 Show All Authors
Authors
  1. Akbarialiabad H1, 2, 3
  2. Jamshidi P4
  3. Aminzade Z4
  4. Azizi N5
  5. Taha SR6
  6. Sadeghian N7
  7. Varghese LJK8, 9, 10
  8. Kouhanjani MF12
  9. Niknam N11
  10. Babocs D13
  11. Elassaad F14
  12. Russomano T15
  13. Murrell DF1, 16, 17
  14. Paydar S18
  15. Bunick CG19
  16. Christiansen R20
  17. Mark Melin M21

Source: Trends in Cancer Published:2025


Abstract

Space science is reshaping oncology by providing novel insights into cancer biology, diagnostics, and therapeutics. The unique space environment – characterized by microgravity and cosmic radiation – induces profound alterations in cancer cell behavior, immune responses, and tumor microenvironment (TME) interactions. These conditions offer a platform for studying cancer progression, enhancing drug discovery, and refining treatment strategies. This opinion article explores microgravity-induced changes in tumor biology, space-driven advancements in imaging and radiation research, and extraterrestrial contributions to cancer therapeutics. By leveraging these innovations, space research holds transformative potential for improving cancer diagnostics and treatment on Earth. © 2025 Elsevier Inc.
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