Does Topical Minoxidil at Concentrations Higher Than 5% Provide Additional Clinical Benefit? Publisher Pubmed



Singh S¹ ; Patil A² ; Kianfar N³ ; Waskielburnat A⁴ ; Rudnicka L⁴ ; Sinclair R⁵ ; Goldust M⁶
Source: Clinical and Experimental Dermatology Published:2022

Abstract

Minoxidil solution is used for the treatment of androgenetic alopecia (AGA). Minoxidil 5% solution has been shown to have superior efficacy to minoxidil 2% solution, it is unknown whether concentrations of minoxidil > 5% provide additional clinical benefit. We performed a review of the literature to examine the evidence on the efficacy and safety of higher concentrations of minoxidil in AGA. A search of the PubMed database was performed using the keywords ‘minoxidil’, ‘androgenic alopecia’ and ‘pattern hair loss’. Relevant articles, including clinical trials, other clinical studies, case series and case reports published in English were considered for review. In addition, relevant references from the bibliography section of the retrieved articles were also reviewed. © 2022 The Authors. Clinical and Experimental Dermatology published by John Wiley & Sons Ltd on behalf of British Association of Dermatologists.